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March 2013 - Hunter New England Health - NSW Government

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Keeping kidneys viable<br />

Dr Paul Trevillian is also a proud advocate of the newly established <strong>Hunter</strong> Transplant<br />

Research Foundation.<br />

The partnership with the <strong>Hunter</strong> Medical Research Institute, the foundation is conducting<br />

translational research into projects that will directly benefit patients undergoing renal<br />

transplantation.<br />

The Foundation has two main goals:<br />

• The first is the investigation of ways to maintain the condition of kidneys from a<br />

deceased donor. For all the advances in transplantation, kidneys still suffer damage<br />

while diffused in cold solutions. The bodies of recipients detect that damage and try to<br />

kill the damaged cells, complicating recovery. The researchers are looking for ways to<br />

mask the damage in donor kidneys to minimise the rejection process in the recipient.<br />

• The second crucial arm of the research involves transplantation tolerance. The team<br />

is looking for ways to give initial treatment to transplant recipients, which would mean<br />

they don’t have to take anti-rejection drugs for the rest of their life.<br />

Potentially, it’s research that will increase the availability of viable donor kidneys and<br />

improve the longer term survival of donor recipients. This research also has the potential<br />

to discover a range of benefits outside of transplantation, assisting patient groups such as<br />

stroke and heart attack victims.<br />

You will hear much more about this ground-breaking team.<br />

f tansplant services dr paul trevillian<br />

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hnehealth.nsw.gov.au 9

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