Hepatitis B

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Methodology 2003: testing for anti-HBc and anti-HBs (titre) anti-HBc HBc+ HBsAg HBV DNA sequencing anti-HBs ≤10mIU/ml administration of 1 booster dose anti-HBs >10mIU/ml considered immune anti-HBs
Conclusions (1) • Coverage with hepatitis B vaccination in infants and adolescents is on average >90%, and exceeds 95% in many areas of Italy • Surveillance on acute hepatitis B cases consistently shows a decline of notifications, especially in the 15-24 years age group • Data from Tuscany and from the rest of Italy show the virtual absence of acute HB cases in subjects belonging to compulsorily vaccinated cohorts who completed the immunization course • Long-term surveillance on children born to HBsAg positive mothers shows the occurrence of a very limited number of asymptomatic infections in vaccinees. . At present, mutant viruses do not pose a threat to universal vaccination programmes in the country 22
Page 1 and 2: Objectives of the presentation Rev
Page 3 and 4: Rationale: Italian strategy for hep
Page 5 and 6: Italian strategy for hepatitis B va
Page 7 and 8: Coverage of infants and adolescents
Page 9 and 10: Study on the incidence of hepatitis
Page 11 and 12: Incidence of acute hepatitis B in s
Page 13 and 14: Epidemiological impact of universal
Page 15 and 16: Hepatitis B vaccination: persistenc
Page 17: Study population (2) 521 Italian re

Hepatitis B

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