OMT - cardioegypt2011

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Pharmacologic Optimal Medical Therapy • Anti-platelet: aspirin; clopidogrel in accordance with established practice standards • Statin: simvastatin ± ezetimibe or ER niacin • ACE Inhibitor or ARB: lisinopril or losartan • Beta-blocker: long-acting metoprolol • Calcium channel blocker: amlodipine R&M Solutions • Nitrate: isosorbide 5-mononitrate Applied to Both Arms by Protocol and Case-Managed www.rmsolutions.net
Lifestyle Optimal Medical Therapy • Smoking cessation • Exercise program • Nutrition counseling • Weight control R&M Solutions Applied to Both Arms by Protocol and Case-Managed www.rmsolutions.net
Page 1 and 2: The COURAGE Trial; When optimal med
Page 3 and 4: COURAGGE is not PCI Vs. OMT PCI add
Page 5 and 6: A North American Trial 19 US Non-VA
Page 7 and 8: Primary Outcome Death or Nonfatal M
Page 9: Smoking Risk Factor Goals Variable
Page 13 and 14: 1.0 0.9 0.8 0.7 0.6 0.5 0.0 Number
Page 15 and 16: 1.0 0.9 0.8 0.7 0.6 0.5 0.0 Number
Page 17 and 18: Conclusions (Courage initial study)
Page 19 and 20: Even if PCI added to OMT did not af
Page 21 and 22: Freedom from Angina During Long-Ter
Page 23 and 24: R&M Solutions www.rmsolutions.net
Page 31 and 32: The “Truth and Consequences” of
Page 33 and 34: Ischemia Reduction ‡ 5% 50 40 30
Page 35 and 36: Is this significant releive of isch
Page 37 and 38: Death or MI rate (%) Rates of Death
Page 39 and 40: Conclusions (Courage nuclear substu
Page 41 and 42: Any confirmation from another RCT R
Page 45 and 46: This when OMT including life style
Page 47 and 48: Many Patients in Need of Lipid Lowe
Page 49 and 50: Many Patients that are Treated are
Page 51 and 52: Situation for hypertension R/ is no
Page 53 and 54: Awareness, Treatment, and Control o
Page 55 and 56: Poor Blood Pressure Control is Scot
Page 57 and 58: MR FIT: CHD Deaths Associated with
Page 59 and 60: Is there really change in clinical
Page 61 and 62:
• As being very much COURAGE-type
Page 63 and 64:
R&M Solutions www.rmsolutions.net
Page 65 and 66:
“We, as a cardiology community, h
Page 67 and 68:
Thank U 4 your attention R&M Soluti
Page 69 and 70:
Conclusions • As an initial manag
Page 71:
Question & Answer R&M Solutions www
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OMT - cardioegypt2011

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