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Risk and Predictors of HCC in People Less than 40 years of Age ...

Risk and Predictors of HCC in People Less than 40 years of Age ...

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Study Population<br />

• Source data: the R.E.V.E.A.L.-HBV study cohort<br />

(N=3,653)<br />

– Population-based prospective study with a mean follow-up <strong>of</strong><br />

11 <strong>years</strong><br />

– Subjects aged 30–65 <strong>years</strong><br />

– At study entry, subjects:<br />

1) provided <strong>in</strong>formed consent;<br />

2) provided a serum sample which was separated on the day<br />

<strong>of</strong> collection <strong>and</strong> frozen at -70ºC;<br />

3) underwent a structured <strong>in</strong>terview by a tra<strong>in</strong>ed public health<br />

nurse;<br />

4) had an ultrasound exam<strong>in</strong>ation<br />

– HBsAg-positive <strong>and</strong> anti-HCV-negative

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