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Methods: Inclusion Criteria • Age 30 or older seen by EMS for symptoms consistent with ACS • Paramedic judgment that clinical picture suggests ACS/AMI and prehospital 12-lead ECG has at least one of the following: – ACI-TIPI predicted probability of ACS of 75% or more – Thrombolytic predictive instrument (TPI) detection of STEMI – STEMI identified based on local EMS protocol
Methods: Exclusion Criteria • HF evidenced by rales more than halfway up lung fields • End stage renal failure requiring dialysis • Language barrier or inability to understand informed consent • Patient known to be pregnant
Page 1 and 2: Results of the IMMEDIATE (Immediate
Page 3 and 4: Carl Apstein, MD, FACC The IMMEDIAT
Page 5 and 6: Background: Rationale for Placebo-C
Page 7 and 8: Methods: Basic Features of Study De
Page 9: Methods: Pre-Specified Endpoints
Page 13 and 14: Methods: Analysis • Sample size c
Page 15 and 16: Results: Screening and Enrollment o
Page 17 and 18: Results: Time from Ischemic Symptom
Page 19 and 20: Results: ITT Cohort Hospital and 30
Page 21 and 22: Results: ITT Cohort Hospital and 30
Page 23 and 24: Results: Cohort Presenting with ST
Page 25 and 26: Results: Cohort Presenting with ST
Page 27 and 28: Median infarct size (IQR) Results:
Page 29 and 30: Median infarct size (IQR) Results:
Page 31 and 32: Limitations • Primary endpoint pr
Page 33 and 34: James Atkins • Assaad Sayah • M

Slides - Clinical Trial Results .org

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