BIOC 3713 - Biochemistry I - Biochemistry and Molecular Biology ...

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BIOC 3713 (Fall 2011): Tentative Schedule of Lectures and Exams Date Lecture Text (chapter.section) Aug 23 1. Introduction. Chemistry review. Assessment quiz. 1.1 – 1.4 Aug 25 2. Protein composition and structure 2.1 – 2.3 Aug 30 3. Protein composition and structure 2.4 – 2.6 Sept 1 4. Exploring proteins and proteomes 3.1 – 3.3 Sept 6 5. Exploring proteins and proteomes 3.4 – 3.6 Sept 8 6. DNA, RNA, and the flow of genetic information 4.1 – 4.2 Sept 13 7. DNA, RNA, and the flow of genetic information 4.3 – 4.4 Sept 15 Mid-Exam 1 (Lectures 1–7; Text 1.1–4.4) Sept 20 8. Introduction to RNA synthesis 4.5, 4.7, 29.1 Sept 22 9. Introduction to protein synthesis 4.6, 30.1 Sept 27 10. Introduction to protein synthesis 30.2 – 30.4 Sept 29 11. Exploring genes and genomes 5.1 – 5.2 Oct 4 12. Exploring genes and genomes 5.3 – 5.4 Oct 6 13. Exploring evolution and bioinformatics 6.1 – 6.3 Oct 11 14. Exploring evolution and bioinformatics 6.4 – 6.5 Oct 13 Mid-Exam 2 (Lectures 8–14; Text 4.5–6.5, 29.1, 30.1–30.3) Oct 18 15. Hemoglobin: Portrait of a protein in action 7.1 – 7.2 Oct 20 16. Hemoglobin: Portrait of a protein in action 7.3 – 7.4 Oct 25 17. Enzymes: Basic concepts and kinetics 8.1 – 8.3 Oct 27 18. Enzymes: Basic concepts and kinetics 8.3 – 8.6 Nov 1 19. Catalytic strategies 9.1 – 9.4 Nov 3 20. Regulatory strategies 10.1 – 10.4 Nov 8 Mid-Exam 3 (Lectures 15–20; Text 7.1–10.4) Nov 10 21. Carbohydrates 11.1 – 11.4 Nov 15 22. Lipids and cell membranes 12.1 – 12.3 Nov 17 23. Lipids and cell membranes 12.4 – 12.6 Nov 22 24. Membrane channels and pumps 13.1 – 13.3 Nov 24 Thanksgiving (no class) Nov 29 24. Membrane channels and pumps 13.4 – 13.6 Dec 1 26. Signal transduction pathways 14.1 – 14.5 Dec 6 Mid-Exam 4 (Lectures 21–26; Text 11.1 – 14.5) Dec 8 Review Dec 13 Final Exam (Cumulative): 10:30AM in 348B NRC Page 2 of 5
Exams: There will be four mid-term exams during the semester, during regular class time. These exams will test you primarily on material that was covered in my lectures and homework assignments. They may also include some material from the textbook. The previous page indicates the topics that will be covered on each mid-term exam. The final exam will be cumulative, covering all material. To give you an idea of what you can expect, the exam questions will resemble the homework assignments. Questions will ask you to recall specific facts such as definitions, names, chemical structures, and reactions. They will test your understanding of biochemistry and your ability to reason and compute solutions of biochemical problems, given specific information. To receive credit, you must respond both intelligibly and legibly to each question. During each exam, you will not be permitted to use any outside information, including your textbook, paper notes, computers, phones, etc. A calculator will only be allowed on certain exams, which I will indicate to you. Your top three exam scores will be used in computing your final grade for the course. There will not be any makeup exams. If you miss an exam, your grade will be determined from your remaining three exams. Homework: To give you exercise your understanding of biochemistry, I will assign approximately five sets of homework problems. I will announce these assignments and post them on D2L. You are encouraged to work together in study groups on these problems. However, your answers to these problems should be written in your own words. Problems that involve calculations should include all of your reasoning to arrive at your numerical answer. Attendance: Your attendance of the lectures is important for you to effectively master biochemistry. Although attendance is not strictly required, I am required to report attendance history, so I will take a daily class roll. Starting the second week of class, I will circulate a list of names. You will sign beside your own name. Make sure you sign in every day, and only sign your own name. Grading Scheme: points total points 3 mid-term exams (top scores): 200 600 5 homework assignments: 20 100 final exam: 300 300 course: 1000 You must earn at least 900 points to make an A, at least 800 points to make a B, at least 650 points to make a C, and at least 500 points to make a D. How to earn an A in this course: Biochemistry is a challenging subject to master. It combines reasoning skills in chemistry, mathematics, and logic with the complexity of biology at the molecular level. Fundamentally, living processes do obey the laws of chemistry and physics. This is the particular power of learning biochemistry. Therefore, this course will build up from atoms to building blocks (amino acids, nucleotides, sugars, and lipids) of biological polymers (proteins, nucleic acids, carbohydrates, and fats). Ultimately, biochemistry has to be presented in the context of cells, organs, and organisms. While it is almost impossible to remember every fact in the text and lectures, I do expect you to know important chemical structures, reactions, and biochemical pathways. I will points these out to you in lectures as the course progresses, so that you will know what to study for each exam. More importantly, you should strive to understand the chemical logic of biological molecules and reactions. Biochemistry is very much an experimental science, still under rapid development. You will hear about Page 3 of 5
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BIOC 3713 - Biochemistry I - Biochemistry and Molecular Biology ...

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