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One of these systematic reviews reported significant publication bias, which the authors suggested<br />

was primarily due to under-reporting of studies with statistically non-significant effects and with<br />

negative effects. [2] Clinical trial registries (included the World Health Organisation Clinical Trials<br />

Registry, the US government’s ClinicalTrials.gov and the Australian New Zealand Clinical Trials<br />

Registry) were searched but did not identify any extra studies.<br />

Despite the above limitations, it is unlikely that a review of primary studies (rather than of systematic<br />

reviews) would have altered the findings. This is because the studies on homeopathy identified<br />

through this process were generally small and of poor quality (either poorly designed or poorly<br />

done). Due to the poor quality of the evidence base, the Homeopathy Working Committee had to<br />

apply caution when considering the results reported by studies. For some health conditions, this<br />

meant that no conclusion could be made on whether or not homeopathy was effective. For other<br />

conditions, this meant that NHMRC could not be confident that the results reported by studies<br />

were reliable.<br />

NHMRC INFORMATION PAPER<br />

EVIDENCE ON THE EFFECTIVENESS OF HOMEOPATHY FOR TREATING HEALTH CONDITIONS<br />

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