Psychopharmacology: Neurotransmitters, Drugs and Behavior

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Causes Largely unknown -Down’s syndrome link -but strongly inherited forms account for only small proportion -plaques seen in wide variety of disorders acquired by disease (encephalitis, CJD) <strong>and</strong> accident (punchdrunk syndrome)
Treatments 1. ‘Cognitive enhancers’ -Acetylcholinesterase inhibitors to offset loss of cholinergic neurons 2. NMDA antagonists -Memantine -idea here is that part of problem in AD is that chronic release of glutamate prevents NMDA receptors from working properly
Page 1 and 2: Psychopharmacology: Neurotransmitte
Page 3 and 4: Being a neurotransmitter: What does
Page 5 and 6: Catecholamine synthesis -this is no
Page 7 and 8: Catecholamines Noradrenergic pathwa
Page 9 and 10: Serotonin Serotonergic pathways in
Page 11 and 12: Acetylcholine Cholinergic pathways
Page 13 and 14: The fabulous glutamate receptor Act
Page 15 and 16: Peptides •Produced in minute quan
Page 17 and 18: What is a ‘drug’? • A very va
Page 19 and 20: Ways that drugs can agonize • Sti
Page 21 and 22: Schizophrenia Affects about 1/100 p
Page 23 and 24: The dopamine theory of schizophreni
Page 25 and 26: Clinical effectiveness of antipsych
Page 27 and 28: Beyond dopamine New generation anti
Page 29 and 30: Neuropathology in Alzheimer’s dis
Page 31 and 32: Formation of NFT’s
Page 33 and 34: Formation of amyloid plaques Amyloi
Page 35 and 36: Formation of amyloid plaques
Page 37: Basal forebrain involvement Nucleus

Psychopharmacology: Neurotransmitters, Drugs and Behavior

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