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Physiology of the World's Second-Most Popular Drug

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GABA<br />

_<br />

Glut<br />

+<br />

+<br />

Glut<br />

+<br />

Glut<br />

GABA<br />

_<br />

Normal cognition depends on a balance <strong>of</strong> excitatory<br />

and inhibitory synaptic activity:<br />

50% <strong>of</strong> <strong>the</strong> brain’s synapses use Glutamate<br />

40% use GABA (gamma-amino-butyric acid)

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