Enoxaparin in ACS
Enoxaparin in ACS
Enoxaparin in ACS
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Is UFH the choice when us<strong>in</strong>g SK?o SK + S.C. Hepar<strong>in</strong> didn’t improve outcomecompared with hepar<strong>in</strong>oGISSI- 2oISIS- 3o SK + I.V. Hepar<strong>in</strong> didn’t improve outcomeoGUSTO- 1o SK + I.V. Hepar<strong>in</strong> <strong>in</strong>crease the tendency formajor bleed<strong>in</strong>gAMI-SK Study designSTEMI(n=496)SK1.5 MU i.v.1 h+ aspir<strong>in</strong>(30 days)(n=491)<strong>Enoxapar<strong>in</strong></strong>30 mgbolus Angiography Follow-upi.v., thenday 8day 301 mg/kg s.c.q 12 h(3–8 days)(n=252)Placebo(3–8 days)(n=239)Angiographyday 8Follow-upday 30SK: Streptok<strong>in</strong>aseTreatment phaseFollow-up phase