PEDIATRIC ARV DOSING CHART - Grandir
PEDIATRIC ARV DOSING CHART - Grandir
PEDIATRIC ARV DOSING CHART - Grandir
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Pediatric <strong>ARV</strong> dosing chart - September 2008 Protease Inhibitors (PI)<br />
Drug<br />
Level of<br />
recommendation<br />
Strength of tab/cap<br />
(mg) or liquid mg/ml<br />
am pm am pm am pm am pm am pm<br />
3-3.9 kg 1 ml 1 ml<br />
4-4.9 kg 1.5 ml 1.5 ml<br />
5-5.9 kg 1.5 ml 1.5 ml 2 2<br />
6-6.9 kg 1.5 ml 1.5 ml 2 2<br />
7-7.9 kg 1.5 ml 1.5 ml 3 2<br />
8-8.9 kg 1.5 ml 1.5 ml 3 3<br />
9-9.9 kg 1.5 ml 1.5 ml 3 3<br />
10-10.9 kg 2 1 2 ml 2 ml 3 3<br />
11-11.9 kg 2 1 2 ml 2 ml 3 3<br />
12-13.9 kg 2 1 2 ml 2 ml 1 1 4 4<br />
14-16.9 kg 2 2 2.5 ml 2.5 ml 1 1 4 4<br />
17-19.9 kg 2 2 2.5 ml 2.5 ml 1 1 5 5<br />
20-24.9 kg 3 2 3 ml 3 ml 1 1 5 5<br />
25-29.9 kg 3 3 3.5 ml 3.5 ml 2 1 5 5<br />
30-34.9 kg 3 3 4 ml 4 ml 2 1 5 5<br />
>35 kg 4 4 5 ml 5 ml 2 2 5 5<br />
Level of recommendation<br />
Comment<br />
Optimal-ideal<br />
WHO 2008<br />
100mg/25mg 80mg/20mg/<br />
ml<br />
Lop/rit*<br />
(Lopinavir / Ritonavir)<br />
200mg/50mg<br />
Alternative<br />
WHO 2006<br />
200mg/50mg<br />
Alternative WHO 2006 : to be used in case Lop/rit 80mg/20mg/ml &<br />
Lop/rit 100mg/25mg not available<br />
NFV<br />
(Nelfinavir)<br />
Alternative<br />
WHO 2006<br />
250mg<br />
Alternative WHO 2006<br />
: no new<br />
recommendations on<br />
NFV in WHO 2008<br />
simplified dosing<br />
recommendations<br />
* Higher doses of Lop/rit may be required when co-administered with enzyme-inducing drugs such as NVP, EFV, fosamprenavir, rifampicin
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