Proposed Pharmacoeconomics Guideline p to Saudi Food & Drug ...

4. METHODS cont.4.5 Effectiveness– Indicate sources of information (e.g., trials, a metaanalysisof individual trials, literature, expert opinion).– Give details about the quality of evidence on efficacyand effectiveness used in the analysis.– Identify factors that are likely to have an impact oneffectiveness (e.g., adherence, diagnostic accuracy),and describe how these were factored into the analysis.– When short-term outcomes are extrapolated to finaloutcomes, explain casual relationships and techniquesused for the extrapolation.– Describe the strength of the evidence for therelationships and links.