2006 Abstracts - American Contact Dermatitis Society

CUTANEOUS B-CELL PSEUDOLYMPHOMA DUE TOARAPHENYLENEDIAMINEKristina Paley, M.D., Larisa J. Geskin, M.D., Matthew J. Zirwas, M.D.University of Pittsburgh, Department of DermatologyLymphomatoid contact dermatitis is a form of T-cell pseudolymphoma thatwas first described in 1976 by Orbaneja et al. Since that initial report a numberof allergens have been reported to cause this type of pseudolymphoma.We describe a case of cutaneous B-cell pseudolymphoma due toparaphenylenediamine (PPD). Our patient presented with violaceous tumors onthe right temple and left post-auricular area in close proximity to the hairline. Dueto the location of the lesions, history of exposure and pathology the diagnosis ofpseudolymphoma secondary to hair cosmetic allergy was suspected. Patchtesting confirmed allergy to PPD which was present in patient’s hair dye. Alllesions resolved with in 2 months after discontinuation of the PPD.This report underscores the importance of thorough history andobservation when assessing patients with suspected lymphoproliferativeprocesses. Most cases of lymphomatoid contact dermatitis are T-cell predominant,and B-cell pseudolymphoma due to contact allergy is extremely rare. This is, toour knowledge, the first report of paraphenylenediamine induced B-cellpseudolymphoma.19