antioxidant and antimicrobial characteristics of red and brown algae ...

Antioxidant and antimicrobial characteristics ……………………….……………………………………………………….Moreover, G5 (High fat diet + 2 mg redalgae polyphenols) shows also a good result forLDL concentration (66.34) but it with nosignificant difference with those of brown algalwater extract. In this connection, HDLconcentration of G2 was the lowest value (9.98)while the administration of algal water extractenhance the value of HDL in groups G5and G8(24.87and 25.71successively). Total lipids andtriglycerides were in significant difference amongall the tested groups of rats. Both of the groupshad subjected to reduce total lipids amount as aresult of administrated the rats with algal waterextract as polyphenol. These results are inagreement with those reported by Herrero et al.,(2006).Effect of water algae extraction and BHT oraladministration on liver functions (ALT, AST)Results of liver functions for different testedrat groups were shown in Table (4). The rats fedwith high fat diet (G2) exhibited an elevation inserum ALT and AST compared to rat groups fedon the basal diet (G1).This means that there weredecrements in the activities of liver enzymes.Concerning the effect of the algal water extractcontaining polyphenols the activities of serumAST and ALT were reduced.Table (4): Effect of water algae extracs and BHT oral administration on activity of serum AST*andALT* in hypercholesterolemic ratsGroupsALT ( GPT )AST ( GOT )(U/L)(U/L)G1 17.66 a ± 0.84 43.57 f ± 0.32G2 26.55 b ± 0.88 61.00 b ± 0.34G3 21.37 d ± 0.70 52.27 c ± 4.04G4 17.86 f ± 0.66 52.24 c ± 0.34G5 17.55 f ± 0.60 47.16 de ± 0.41G6 23.79 c ± 0.90 48.51 d ± 0.46G7 20.48 d ± 0.73 45.77 e ± 0.51G8 19.45 e ± 0.58 42.26 f ± 0.48G9 34.83 a ± 0.46 76.02 a ± 0.56G1= Basel diet, G2 = High fat diet, G3 = High fat diet + 1mg red algae polyphenols,G4 = High fat diet 1.5 mg red algae polyphenols,G5 = High fat diet + 2 mg red algae polyphenols,G6 = High fat diet + 1mg brown algae polyphenols, G7 = High fat diet +1.5mg brown algae polyphenols,G8 = High fat diet + 2mg brown algae polyphenols, G9 = High fat diet +BHT*Means of each value, within the same column, followed by the same latter is not significantly different at 0.05level.*Each value is followed by its ± standard deviation.On the other hand, data presented in Table (4)showed that rats fed on high fat diet with BHT asa synthetic antioxidant recorded higher values.Such findings were coincided with that found byFarag et al. (2004).Effect of water algae extracts and BHTadministration on concentration of serum Ureaand uric acid in hypercholesterolemic ratsData presented in Table (5) showed an increasein the urea and uric acid levels in group (G2)whose on the high fat diet. The level of such itemsis very closed to that found in (G9) which fed onhigh fat diet plus BHT. The administration of thewater algae extracts resulted in a detectabledownward in such items (urea and uric acid).Those results are in agreement with these foundby Herrero et al. (2006).823