Chem 447 syllabus - Benedict College

2. Describe the buffer selection3. Describe amino acids and proteins4. Describe the molecular structure of proteins5. Understand functional diversity of proteins, myoglobin and hemoglobin6. Outline a general scheme for protein purification and explain techniques7. Understand enzyme catalysis and inhibition8. Define the most abundant biomolecules on earth, carbohydrates9. Discuss the carbohydrate metabolism10. Explain different types of metabolic pathways and ATP formation11. Understand lipids12. Discuss lipid metabolism13. Explain DNA and RNA structure14. Understand DNA replicationMAIN TOPICSI. Introduction to molecular structure of watera. Water is a polar moleculeb. Solvent properties of waterc. Ionization of water, acids and basesd. Buffer selection, Henderson-Hasselbalk equationII. Amino acids and peptidesa. The building blocks of proteinsb. Physiological interest of amino acidsc. Amino acids and proteins as acids and bases/ solving problemsd. Protein structuree. Protein sequencingf. Protein purificationsg. Analytical methods and techniquesh. Enzyme kineticsi. Enzyme inhibitionIII. Carbohydratesa. Aldoses, ketoses, formation of hemiacetalsb. Disaccharides, homopolysaccharides, heteroploysaccharidesc. Glycolysisd. Gluconeogenesis, pentose phosphate pathwaye. Aerobic metabolismf. Oxidative phosphortlationg. Antioxidant systemsIV.lipidsa. Fatty acids, triglycerides, neutral fatsb. Phospholipids and cell membranec. Sterolsd. Lipid metabolisme. Health effect of lipidsV. Nucleic acidsa. DNA and RNA structuresb. Gene expressionc. Polymerses