Plasma Dilution
Plasma Dilution
Plasma Dilution
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Case Presentation #1Discussion• FDA specifically states that calculations providedin the DE Guidance Document are for donorsweighing 45-100kg• The FDA calculations provide a good estimate ofblood/plasma volume for an average sized adult,but are inaccurate for children and obese adults• Other more physiologically appropriatecalculations should be used in these populations• What about males vs. females in the 45-100kgweight range?
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