TROG_2014_ASM-program

TROG 201426th ANNUAL SCIENTIFIC MEETING 14TROG 201415 26th ANNUAL SCIENTIFIC MEETINGTROG - FRO TRAINEE STATISTICS& RESEARCH WORKSHOP1st April 2014, 8.30 to 5.00pm, Wandiny Room8.30 - 8.40am Welcome and IntroductionsTime Topic Content8.40 - 9.20am Study Design Cohort/Case controlAspects of biasPhase I and Phase II designsRandomised controlled trialsRandomisation and StratificationNon-inferiority / equivalence designs9.20 - 10.30am Small Groups Example trial scenarios provided will be used in thissession to explore aspects of phase II and III trial designincluding non-inferioirty and equivalence studies10.30 - 11.00am Morning Tea11.00 - 11.40am Selecting endpoints Outcome to EndpointEndpoint selectionMeasurementof effectMeans, mediansStandard deviation, IQROdds ratiosRisk rateHazard ratios - use example of TROG 02.0211.40 - 12.30pm Small Groups Example trial scenarios provided will be used in thissession to explore aspects of endpoint selection12.30 - 1.20pm Lunch1.20pmInternational Guest Speaker - Prof David Brizel2.30 - 3.00pm Other issues Sample size considerationsNon-complianceConfounders – eg HPV, Quality assurance in H&N RT trialsAppropriate follow up timeFrequency of data collectionDealing with missing data3.00 - 3.30pm Afternoon Tea3.30 - 4.30pm Small Groups Example trial scenarios provided will be used in thissession to explore aspects of sample size calculation,follow-up and interpretation4.30 - 5.00pm Q&AWrap-upThis workshop is sponsored by