Sex selection: choice and responsibility in human reproduction ...
Sex selection: choice and responsibility in human reproduction ...
Sex selection: choice and responsibility in human reproduction ...
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<strong>Sex</strong> Selection: Choice <strong>and</strong> Responsibility <strong>in</strong> Human ReproductionSummaryPreimplantation sex<strong>selection</strong>: pros <strong>and</strong> consPros✓ Established technique✓ Reliable diagnosisCons✗ Invasive <strong>and</strong> disruptive– requires IVFtreatment16✓ Closely regulated <strong>and</strong>monitored <strong>in</strong> the UK✗ May result <strong>in</strong> embryosof the un<strong>in</strong>tended sexbe<strong>in</strong>g produced whichmight then have to bediscarded✗ More expensive thansperm sort<strong>in</strong>gtechniquesComb<strong>in</strong>ed methods49. A third option is to comb<strong>in</strong>e the two approaches discussed above (sperm sort<strong>in</strong>g<strong>and</strong> PGD) <strong>and</strong> to conduct PGD on embryos that have been created with sperm thathas already been sorted <strong>in</strong>to ‘X’ <strong>and</strong> ‘Y’ samples.50. Whilst this approach still requires IVF <strong>and</strong> is likely to be more costly than either ofthe other methods used s<strong>in</strong>gly, it offers the accuracy of PGD with a higher chance ofsuitable embryos be<strong>in</strong>g available for transfer by m<strong>in</strong>imis<strong>in</strong>g the chances thatembryos of the un<strong>in</strong>tended sex will be created <strong>in</strong> the first place. On the other h<strong>and</strong>as only two embryos may be transferred <strong>in</strong> one IVF cycle if more than two eggs arefertilised it may still result <strong>in</strong> more embryos be<strong>in</strong>g created than can be used.Post-implantation sex <strong>selection</strong>51. The oldest methods of sex <strong>selection</strong> are those which <strong>in</strong>volve select<strong>in</strong>g which childrenwill be born by term<strong>in</strong>at<strong>in</strong>g pregnancies where fetuses are shown, through prenataltest<strong>in</strong>g, to be of the undesired sex, or, <strong>in</strong>deed simply kill<strong>in</strong>g new-born <strong>in</strong>fants of theundesired sex (<strong>in</strong>fanticide).52. Term<strong>in</strong>ation of pregnancy on grounds of fetal sex alone is illegal <strong>in</strong> the UK underthe Abortion Act 1967, although <strong>in</strong> cases <strong>in</strong> which there is a serious sex-l<strong>in</strong>keddisease there might be grounds for term<strong>in</strong>at<strong>in</strong>g a pregnancy if the fetus is at risk orif cont<strong>in</strong>u<strong>in</strong>g the pregnancy will risk damag<strong>in</strong>g the mental or physical health of thewoman or other children <strong>in</strong> the family.53. Infanticide is illegal <strong>in</strong> the UK.Human Fertilisation <strong>and</strong> Embryology Authority