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Feline calicivirus infection - The European Advisory Board on Cat ...

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In cats with chr<strong>on</strong>ic stomatitis and FCV <str<strong>on</strong>g>infecti<strong>on</strong></str<strong>on</strong>g>, administrati<strong>on</strong> of modified live FCVvaccine is best avoided (Pedersen et al., 1995; EBM grade IV).<strong>Cat</strong>s receiving corticosteroids or other immunosuppressive drugsIn cats under corticosteroid treatment, vaccinati<strong>on</strong> should be c<strong>on</strong>sidered carefully. Depending<strong>on</strong> dosage and durati<strong>on</strong>, corticosteroids may cause functi<strong>on</strong>al suppressi<strong>on</strong> of cell-mediatedimmune resp<strong>on</strong>ses in particular. In dogs, corticosteroids do not hamper effectiveimmunizati<strong>on</strong> if given for short periods of time at low to moderate doses (Nara et al., 1979),but the effect of corticosteroids <strong>on</strong> vaccine efficacy in cats is not known. Hence the use ofcorticosteroids and/or other immunosuppressants at the time of vaccinati<strong>on</strong> should beavoided.ReferencesAbd-Eldaim M, Potgieter L & Kennedy M (2005). Genetic analysis of feline <str<strong>on</strong>g>calicivirus</str<strong>on</strong>g>esassociated with a hemorrhagic-like disease. J Vet Diagn Invest, 17:420-9.Addie DD, Radford A, Yam PS & Taylor DJ (2003). Cessati<strong>on</strong> of feline calicvirus sheddingcoinciding with resoluti<strong>on</strong> of chr<strong>on</strong>ic gingivostomatitis in a cat. J Small Anim Pract,44(4):172-6.Addie D, Poulet H, Golder MC, McD<strong>on</strong>ald M, Brunet S, Thibault JC, Hosie MJ (2008).Ability of antibodies to two new caliciviral vaccine strains to neutralise feline <str<strong>on</strong>g>calicivirus</str<strong>on</strong>g>isolates from the UK. Vet Rec 163(12):355-7.Bannasch MJ & Foley JE (2005). Epidemiologic evaluati<strong>on</strong> of multiple respiratory pathogensin cats in animal shelters. J <str<strong>on</strong>g>Feline</str<strong>on</strong>g> Med Surg, 7:109-19.Belgard S, Truyen U, Thibault JC, Sauter-Louis C, Hartmann K (2010). Prelevance of feline<str<strong>on</strong>g>calicivirus</str<strong>on</strong>g>, feline immunodeficiency virus, feline leukemia virus, feline herpesvirus andBart<strong>on</strong>ella henselae in cats with chr<strong>on</strong>ic gingivostomatitis. Berl Munch Tierarztl Wochenschr123(9-10):369-76.Bennett D, Gaskell RM, Mills A, Knowles J, Carter S & McArdle F (1989). Detecti<strong>on</strong> offeline <str<strong>on</strong>g>calicivirus</str<strong>on</strong>g> antigens in the joints of infected cats. Vet Rec, 124(13):329-32.Binns SH, Daws<strong>on</strong> S, Speakman AJ, Cuevas LE, Hart CA, Gaskell CJ, Morgan KL & GaskellRM (2000). A study of feline upper respiratory tract disease with reference to prevalence andrisk factors for <str<strong>on</strong>g>infecti<strong>on</strong></str<strong>on</strong>g> with feline <str<strong>on</strong>g>calicivirus</str<strong>on</strong>g> and feline herpesvirus. J <str<strong>on</strong>g>Feline</str<strong>on</strong>g> Med Surg,2:123-33.Brunet S, Jas D, David F, Bublot M & Poulet H. (2005). <str<strong>on</strong>g>Feline</str<strong>on</strong>g> <str<strong>on</strong>g>calicivirus</str<strong>on</strong>g>: vaccinati<strong>on</strong>sagainst virulent strains. In Comparative and emerging virus <str<strong>on</strong>g>infecti<strong>on</strong></str<strong>on</strong>g>s of dogs and cats.C<strong>on</strong>ference of the <str<strong>on</strong>g>European</str<strong>on</strong>g> Society of Veterinary Virology 2005, Liverpool.Clay S, Maherchandani S, Malik YS & Goyal SM (2006). Survival <strong>on</strong> uncomm<strong>on</strong> fomites offeline <str<strong>on</strong>g>calicivirus</str<strong>on</strong>g>, a surrogate of noroviruses. Am J Infect C<strong>on</strong>trol, 34:41-3.Coutts AJ, Daws<strong>on</strong> S, Willoughby K & Gaskell RM (1994). Isolati<strong>on</strong> of feline respiratoryviruses from clinically healthy cats at UK cat shows. Vet Rec, 135:555-556.

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