005-2011 Nurse's Drug Handbook, 10th Edition-Jones & Bartlett Learning-0763792381-Jones & Bartlet

tion of beta 2 receptors in the lungs and maycause bronchoconstriction.ContraindicationsCardiogenic shock, heart failure unlessfrom tachyarrhythmia, hypersensitivity toacebutolol, overt heart failure, second- andthird-degree heart block, severe bradycardiaInteractionsDRUGSalpha agonists, nasal decongestants:Increased risk of hypertensionaluminum salts, barbiturates, calcium salts,cholestyramine, colestipol, indomethacin,NSAIDs, penicillins, rifampin, salicylates,sulfinpyrazone: Decreased antihypertensiveeffectsanticholinergics, hydralazine, methyldopa,prazosin, reserpine: Increased risk of bradycardiaand hypotensionbeta 2 agonists, theophylline: Decreased bronchodilationepinephrine: Increased risk of blocked sympathomimeticeffectsergot alkaloids: Increased risk of peripheralischemia and gangreneflecainide: Possibly increased effects of bothdrugslidocaine: Possibly increased serum lidocainelevel, causing toxicityoral contraceptives, quinidine: Possiblyincreased serum acebutolol levelsulfonylureas: Possibly decreased hypoglycemiceffectsverapamil: Increased cardiac effects, leadingto bradycardia and hypotensionAdverse ReactionsCNS: Abnormal dreams, anxiety, confusion,depression, dizziness, fatigue, fever, headache,insomniaCV: Bradycardia, chest pain, edema, heartblock, heart failure, hypotensionEENT: Abnormal vision, conjunctivitis, dryeyes, eye pain, pharyngitis, rhinitisGI: Constipation, diarrhea, flatulence,hepatotoxicity, indigestion, nauseaGU: Dysuria, impotence, polyuriaMS: Arthralgia, myalgiaRESP: Bronchospasm, cough, dyspnea,wheezingSKIN: RashNursing Considerations• Before therapy begins, obtain baselineacetaminophen 23renal function tests, as ordered.• Check apical and radial pulses before givingacebutolol. Also, frequently monitorblood pressure and pulse rate, rhythm,and quality during treatment.• Give drug with food to prevent GI upset.• Acebutolol may elevate uric acid, potassium,triglyceride, lipoprotein, and antinuclearantibody levels; it also may interferewith accuracy of glucose tolerance tests.• Monitor diabetic patient’s blood glucoselevel to spot alterations.• Notify prescriber if you detect a heart ratebelow 50 beats/min or signs of heart failure,such as dyspnea, crackles, unexplainedweight gain, and jugular vein distention.• Monitor patient for peripheral edema, andevaluate fluid intake and output.PATIENT TEACHING• Tell patient that tablets may be crushed orswallowed whole.• Warn against stopping acebutolol abruptlybecause doing so could cause angina ordangerously high blood pressure.• Instruct patient to take a missed dose assoon as possible up to 6 hours before nextscheduled dose but not to double the nextdose.• Advise patient to consult prescriber beforetaking OTC drugs that contain alpha agonists,such as nasal decongestants and coldpreparations.• Instruct patient to report dizziness, confusion,and fever immediately.• Urge patient to maintain diet and lifestylechanges to help control blood pressure.acetaminophenAbenol (CAN), Acephen, Aceta Elixir,Acetaminophen Uniserts, Aceta Tablets,Apacet Capsules, Apacet Elixir, ApacetExtra Strength Tablets, Apacet RegularStrength Tablets, Aspirin Free PainRelief, Exdol (CAN), Feverall, FeverallSprinkle Caps, Genapap Infants’ Drops,Genebs Extra Strength, HalenolChildren’s Junior Strength, LiquiprinElixir, Liquiprin Infants’ Drops, MedaCap, Neopap, Oraphen-PD, Panadol,Panadol Infants’ Drops, Pediaphen,Redutemp, Robigesic (CAN), St. JosephAspirin-Free Infant Drops, TapanolA