Several flavonoids from Capsella bursa-pastoris (L.) Medic.

Several flavonoids from Capsella bursa-pastoris (L.) Medic./ Asian Journal of Traditional Medicines, 2007, 2 ( 5 )3.35~3.63 (m), 1.12 (3H, d, J = 6.2 Hz, H-6″ ). Alldata were identical with that of kaempferol-7-O-α-Lrhamnopyranoside[11] .-Compound 5Yellow amorphous powder, mp 231-232 ºC. 1 HNMR δ (300 MHz, DMSO-d 6) 12.64 (1H, s, 5-OH),7.59 (1H, d, J = 2.5 Hz, H-2′), 7.57 (1H, dd, J = 8.5,2.5 Hz, H-6′), 6.84 (1H, d, J = 8.7 Hz, H-5′), 6.40 (1H,d, J = 2.5 Hz, H-8), 6.20 (1H, d, J = 2.5 Hz, H-6), 5.47(1H, d, J = 6.9 Hz, H-1″), 5.4~3.0 (10H, m, glc). Alldata were identical with that of quercetin-3-O-β-Dglucopyranoside[12] .-Compound 6Yellow amorphous powder, mp 242-244 ºC, HCl-Mg reaction: positive, Molish reaction: positive. UVλ(max) nm: 255, 270, 348 (MeOH). 1 H NMR δ (300MHz, DMSO-d 6) 13.56 (1H, s, 5-OH), 7.42 (1H, d,J = 2.5 Hz, H-2′), 7.39 (1H, dd, J = 8.5, 2.5 Hz, H-6′), 6.86 (1H, d, J = 8.1 Hz, H-5′), 6.65 (1H, br.s, H-3),6.48 (1H, br.s, H-8), 4.59 (1H, d, J = 9.7 Hz, H-1″), 4.1~3.0 (10H, m, glc). 13 C NMR δ (75 MHz,DMSO-d 6) 163.4 (C-2), 102.8 (C-3), 181.9 (C-4),156.2 (C-5), 108.9 (C-6), 163.7 (C-7), 93.6 (C-8),160.7 (C-9), 103.4 (C-10), 118.9 (C-1′), 113.3 (C-2′), 145.8 (C-3′), 149.8 (C-4′), 116.1 (C-5′), 121.4 (C-6′), 73.1 (C-1″), 70.7 (C-2″), 78.9 (C-3″), 70.3 (C-4″),81.6 (C-5″), 61.5 (C-6″). All data were identical withthat of quercetin-6-C-β-D- glucopyranoside [13] .-Compound 7Yellow amorphous powder, HCl-Mg reaction:positive, Molish reaction: positive. 1 H NMR δ (300MHz, DMSO-d 6) 8.08 (2H, d, J = 8.8 Hz , H-2′, 6′), 6.90 (2H, d, J = 8.8 Hz , H-3′, 5′), 6.83 (H-8), 6.44(H-6), 5.55 (1H, br.s, H-1″′), 5.47 (1H, d, J = 7.2 Hz,H-1″), 1.10 (3H, d, J = 6.4 Hz, -CH3). 13 C NMR δ(75 MHz, DMSO-d 6) 177.8 (C-4), 161.6 (C-7), 160.9(C-5), 156.8 (C-2), 156.0 (C-9), 133.5 (C-3), 131.1(C-2′, C-6′), 120.8 (C-1′), 115.3 (C-3′, C-5′), 160.3(C-4′), 105.7 (C-10), 98.5 (C-6), 94.5 (C-8), 100.8(C-1″), 77.7 (C -5″), 76.5 (C-3″), 74.3 (C-2″), 70.2(C-4″), 60.9 (C-6″), 99.5 (C-1″′), 71.7 (C-4″′), 70.1(C-3″′), 70.0 (C-2″′), 69.7 (C-5″′), 18.0 (C-6″′). Alldata were identical with that of kaempferol-3-O-β-Dglucopyranosyl-7-O-α-L-rhamnopyranoside[14] .-Compound 8Yellow amorphous powder, HCl-Mg reaction:positive, Molish reaction: positive. 1 H NMR δ (300MHz, DMSO-d 6) 12.64 (1H, s, 5-OH), 7.62 (1H, d,J = 2.5 Hz, H-2′), 7.60 (1H, dd, J = 8.5, 2.5 Hz, H-6′), 6.85 (1H, d, J = 8.5 Hz, H-5′), 6.80 (1H, d, J = 2.5Hz, H-8), 6.43 (1H, d, J = 2.5 Hz, H-6), 5.49 (1H, d,J = 6.9 Hz, H-1″), 5.55 (1H, s, H-1″′), 5.4~3.0 (17H,m, glc and rha), 1.12 (3H, d, J = 6.0 Hz, -CH3). 13 CNMR δ (75 MHz, DMSO-d 6) δ156.8 (C-2), 133.7(C-3), 177.7 (C-4), 160.9 (C-5), 99.5 (C-6), 161.7(C-7), 94.4 (C-8), 156.8 (C-9), 105.7 (C-10), 121.8(C-1′), 115.3 (C-2′), 145.0 (C-3′), 148.9 (C-4′), 116.4(C-5′), 121.1 (C-6′), 100.8 (C-1″), 74.2 (C-2″), 76.6(C-3″), 70.3 (C-4″), 77.8 (C-5″), 61.1 (C-6″), 99.5(C-1″′), 70.0 (C-2″′), 70.2 (C-3″′), 71.7 (C-4″′), 69.9(C-5″′), 18.0 (C-6″′). All data were identical withthat of quercetin-3-O-β-D-glucopyra- nosyl-7-O-α-Lrhamnopyranoside[15] .-Compound 9Yellow amorphous powder, HCl-Mg reaction:positive, Molish reaction: positive. UV λ(max)nm: 225, 270, 350 (MeOH). 1 H NMR δ (300 MHz,DMSO-d 6,) 7.98 (2H, d, J = 8.7 Hz, H-2′, 6′), 6.88(2H, d, J = 8.7 Hz, H-3′, 5′), 6.40 (1H, br.s, H-8), 6.20(1H, br.s, H-6), 5.30 (1H, d, J = 6.9 Hz, H-1″), 4.39(1H, br.s, H-1″′), 3.0~4.0 (16H, rut), 1.10 (3H, d, J= 6.4 Hz, -CH3). 13 C NMR δ (75 MHz, DMSO-d 6)156.4 (C-2), 133.1 (C-3), 177.2 (C-4), 161.1 (C-5),98.7 (C-6), 164.0 (C-7), 93.7 (C-8), 156.7 (C-9), 103.7(C-10), 120.7 (C-1′), 130.7 (C-2′, C-6′), 115.0 (C-3′, C-5′), 159.8 (C-4′) , 101.3 (C-1″), 74.1 (C-2″), 76.3(C-3″), 69.8 (C-4″), 75.6 (C-5″), 66.8 (C-6″), 100.7(C-1″′), 70.2 (C-2″′), 70.5 (C-3″′), 71.7 (C-4″′), 68.1(C-5″′), 17.6 (C-6″′). All data were identical with that220