Diagnosis and Classification of the Schizophrenia Spectrum Disorders

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ContentsForewordSchizophrenia Spectrum Disorders: Insights from Views Across100 years .................................... vMichael S. Ritsner1 The Schizophrenia Construct After 100 Years of Challenges ... 1Michael S. Ritsner and Irving I. Gottesman2 Diagnosis and Classification of the SchizophreniaSpectrum Disorders .......................... 45Daniel Mamah and Deanna M. Barch3 Toward a Multidimensional Continuum Modelof Functional Psychoses for Research Purposes ........... 85Michael S. Ritsner4 Irving Gottesman and the Schizophrenia Spectrum ........ 115Aksel Bertelsen5 Schizotypy: Reflections on the Bridge to Schizophreniaand Obstacles on the Road Ahead to Etiologyand Pathogenesis ............................ 127Mark F. Lenzenweger6 Autistic Spectrum Disorders and Schizophrenia .......... 143Yael Dvir, Vishal Madaan, Lauren Yakutis, Jean A. Frazier,and Daniel R. Wilson7 One Hundred Years of Insanity: Genomic, Psychological,and Evolutionary Models of Autism in Relationto Schizophrenia ............................ 163Bernard J. Crespi8 Quantifying the Dynamics of Central SystemicDegeneration in Schizophrenia .................... 187Anca R. Rădulescuix
xContents9 Schizophrenia Has a High Heritability, but Where Arethe Genes? ................................ 219Patrick P. McDonald and Shiva M. Singh10 Changes in Gene Expression in Subjectswith Schizophrenia Associated with Disease Progression ...... 237Brian Dean, Andrew Gibbons, Elizabeth Scarr,and Elizabeth A. Thomas11 Amino Acids in Schizophrenia – Glycine, Serineand Arginine .............................. 253Glen B. Baker, Jaime E.C. Hallak, Alexandria F. Dilullo,Lisa Burback, and Serdar M. Dursun12 Developmental Consequences of Prenatal Exposureto Maternal Immune Activation .................... 263Stefanie L. Bronson and Neil M. Richtand13 Glutamatergic Neurotransmission Abnormalities andSchizophrenia .............................. 287Yogesh Dwivedi and Ghanshyam N. Pandey14 Mathematical Models in Schizophrenia ............... 305Zhen Qi, Gary W. Miller, and Eberhard O. Voit15 Methamphetamine-Associated Psychosis: A Model forBiomarker Discovery in Schizophrenia ................ 327Chad A. Bousman, Stephen J. Glatt, Ian P. Everall,and Ming T. Tsuang16 What Does Proteomics Tell Us About Schizophrenia? ....... 345Daniel Martins-de-Souza, Wagner F. Gattaz,and Emmanuel Dias-Neto17 The Role of 3α-Hydroxy-5α-Pregnan-20-One in Mediatingthe Development and/or Expression of SchizophreniaSpectrum Disorders: Findings in Rodents Modelsand Clinical Populations ........................ 367Cheryl A. Frye and Danielle C. Llaneza18 Neural Substrates of Emotion Dysfunctions in Patientswith Schizophrenia Spectrum Disorders ............... 405Katharina D. Pauly and Ute Habel19 Brain Morphological Abnormalities at the Onset ofSchizophrenia and Other Psychotic Disorders: A Reviewof the Evidence ............................. 431Antonio Vita, Luca De Peri, Cesare Turrina, and Emilio Sacchetti20 Mapping Prodromal Psychosis .................... 445Paolo Fusar-Poli, Stefan Borgwardt, and Philip McGuire
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Page 5 and 6: EditorMichael S. RitsnerTechnion -
Page 7 and 8: viForewordpsychotic disorders, gene
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1 The Schizophrenia Construct After
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Chapter 2Diagnosis and Classificati
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2 Diagnosis and Classification of t
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86 M.S. RitsnerKeywords Functional
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88 M.S. RitsnerProof-of-Concept for
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90 M.S. RitsnerTable 3.1 Measuring
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92 M.S. RitsnerTable 3.2 Definition
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94 M.S. RitsnerFactor Structure: Th
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96 M.S. RitsnerFig. 3.4 Frequency o
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98 M.S. RitsnerPatients Sex Age(yr.
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100 M.S. RitsnerTable 3.4 Frequency
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102 M.S. Ritsner1. A genetic load h
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104 M.S. Ritsnerneuronal function a
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106 M.S. RitsnerMulti-dimensional p
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108 M.S. Ritsner39. Fink M (2009) C
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110 M.S. Ritsner82. Walsh T, McClel
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112 M.S. Ritsner125. Kissling W, He
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Chapter 4Irving Gottesman and the S
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4 Irving Gottesman and the Schizoph
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128 M.F. LenzenwegerKeywords Schizo
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130 M.F. LenzenwegerReactionsSchizo
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132 M.F. Lenzenwegerorganize resear
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134 M.F. Lenzenwegerdone recently b
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136 M.F. Lenzenwegerwith a “story
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138 M.F. Lenzenwegernot be true (se
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140 M.F. Lenzenweger3. Rado S (1960
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Chapter 6Autistic Spectrum Disorder
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6 Autistic Spectrum Disorders and S
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Chapter 7One Hundred Years of Insan
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7 One Hundred Years of Insanity 165
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188 A.R. Rădulescutreatment can be
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190 A.R. Rădulescupathways have no
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192 A.R. Rădulescukey functions re
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194 A.R. Rădulescuincreasing insta
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196 A.R. Rădulescucorrections of t
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198 A.R. RădulescuQuantifying Schi
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200 A.R. RădulescuTable 8.1 Profil
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202 A.R. RădulescuFig. 8.4 Princip
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204 A.R. RădulescuFig. 8.5 Charact
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206 A.R. Rădulescuto use discrete
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208 A.R. RădulescuAppendix 1: Simp
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210 A.R. RădulescuStudy design, ta
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212 A.R. Rădulescu35. Kitzbichler
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214 A.R. Rădulescu83. Shibata T, T
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216 A.R. Rădulescu132. Rosenkranz
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Chapter 9Schizophrenia Has a High H
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9 Schizophrenia Has a High Heritabi
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Chapter 10Changes in Gene Expressio
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10 Changes in Gene Expression 239ge
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10 Changes in Gene Expression 241Ta
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10 Changes in Gene Expression 243fu
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10 Changes in Gene Expression 245ex
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10 Changes in Gene Expression 247el
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10 Changes in Gene Expression 24941
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10 Changes in Gene Expression 25184
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254 G.B. Baker et al.fMRIGABAGTIHPL
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256 G.B. Baker et al.[20-26]. Glyci
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258 G.B. Baker et al.suggesting bot
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260 G.B. Baker et al.14. Labrie V,
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262 G.B. Baker et al.54. Palsson E,
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264 S.L. Bronson and N.M. RichtandA
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266 S.L. Bronson and N.M. Richtandt
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268 S.L. Bronson and N.M. RichtandP
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270 S.L. Bronson and N.M. Richtandi
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272 S.L. Bronson and N.M. RichtandB
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274 S.L. Bronson and N.M. Richtandm
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276 S.L. Bronson and N.M. RichtandG
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278 S.L. Bronson and N.M. RichtandB
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280 S.L. Bronson and N.M. Richtandp
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282 S.L. Bronson and N.M. Richtand3
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284 S.L. Bronson and N.M. Richtand8
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Chapter 13Glutamatergic Neurotransm
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13 Glutamatergic Neurotransmission
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Chapter 14Mathematical Models in Sc
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14 Mathematical Models in Schizophr
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328 C.A. Bousman et al.Introduction
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330 C.A. Bousman et al.prolonged. B
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332 C.A. Bousman et al.Biomarker Di
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334 C.A. Bousman et al.Table 15.3 G
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336 C.A. Bousman et al.precision th
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338 C.A. Bousman et al.15. United N
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340 C.A. Bousman et al.60. Ikeda M,
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342 C.A. Bousman et al.98. Scott JC
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Chapter 16What Does Proteomics Tell
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16 What Does Proteomics Tell Us Abo
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Chapter 17TheRoleof3α-Hydroxy-5α-
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17 The Role of 3α-Hydroxy-5α-Preg
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Chapter 18Neural Substrates of Emot
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18 Neural Substrates of Emotion Dys
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432 A. Vita et al.AbbreviationsBD B
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434 A. Vita et al.Bipolar DisorderA
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436 A. Vita et al.temporale, and ca
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438 A. Vita et al.Among the many po
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440 A. Vita et al.22. Hietala J, Ca
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442 A. Vita et al.60. Peters BD, de
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Chapter 20Mapping Prodromal Psychos
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20 Mapping Prodromal Psychosis 447i
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20 Mapping Prodromal Psychosis 449t
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20 Mapping Prodromal Psychosis 451F
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20 Mapping Prodromal Psychosis 453s
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20 Mapping Prodromal Psychosis 457o
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20 Mapping Prodromal Psychosis 459N
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20 Mapping Prodromal Psychosis 461T
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20 Mapping Prodromal Psychosis 465p
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20 Mapping Prodromal Psychosis 4673
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474 Afterwordon the current paradig
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476 Afterwordpsychiatric disorders
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478 Contents to Volume II10 Schizop
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480 Contents to Volume III10 Revisi
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482 Contributors to Volume IIRuth C
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484 Contributors to Volume IIGary R
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Contributors to Volume IIIAnthony O
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Contributors to Volume III 489Jenni
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IndexAAcute transient psychosis, 5,
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Index 493Impairment, 7, 18, 20-22,
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Diagnosis and Classification of the Schizophrenia Spectrum Disorders

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