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Tolerance of Anemia in Pediatrics - SABM - Patient Blood ...

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Kirpalani: (PINT) Trial (2006)• 451 ELBW, 770gm, high vs low threshold• No difference <strong>in</strong> death, ROP, BPD, bra<strong>in</strong> <strong>in</strong>jury• Low Hb gp (89% transfused, 3.7 donors)High Hb gp (95% transfused, 4.2 donors)• Number <strong>of</strong> transfusions (4.9 vs. 5.7 ,P0.07)Mean eventual Hb difference (1.1 gm)No difference <strong>in</strong> NDI at 18-22 m (low 45%, high 39%)Whyte Kirpalani <strong>Pediatrics</strong> (2006) 123 (1): 207-13

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