CLS 422 Clinical Immunohematology I Take Home Quiz Day Two ...

20. The main difference between the direct antiglobulin test (DAT) and the indirect
antiglobulin test (IAT) is:
a. Sensitization takes place in the test system in the indirect antiglobulin test
and in the body in the DAT.
b. Specimen for the DAT is either the patient’s cells or serum whereas the
IAT only uses the patient’s serum.
c. The IAT detects only IgG antibodies whereas the DAT detects IgG and
complement.
d. Use of enhancement reagents is required in the IAT but not in the DAT.
21. Which of the following specimens is the best to use for a direct antiglobulin test?
a. Clot tube with gel separator
b. Clot tube, no gel, stored overnight at 1-6C
c. EDTA
d. Any plasma specimen will work equally well.
22. When investigating a positive DAT, it is important to get an accurate patient
history which includes: (More than one correct answer)
a. ABO & Rh
b. Diagnosis
c. Medications
d. Transfusions
23. In a hemolytic transfusion reaction, the patient has:
a. An allergy to a protein in the donor plasma.
b. Bacteria in the blood stream, due to contamination of donor blood.
c. An antibody directed against antigens on the donor’s leukocytes.
d. An antibody directed against antigens on the donor’s red blood cells.
24. In Hemolytic Disease of the Fetus and Newborn (HDFN), a positive DAT
indicates that the:
a. Infant’s RBCs are coated with maternal antibody.
b. Mother’s RBCs are coated with fetal antibody.
c. Infant’s RBCs are coated with paternal antibody.
d. Mother’s RBCs are in the infant’s circulation.
CLS 422 Clinical Immunohematology I Page 5 of 6
Student Lab Day Two Take Home Quiz