denosumab treatment results in significant trabecular and cortical ...
denosumab treatment results in significant trabecular and cortical ...
denosumab treatment results in significant trabecular and cortical ...
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QCT Percent Change <strong>in</strong> Hip BMD <strong>and</strong> BMCSubregions at Month 36BMD (mg/cm 3 )PlaceboDenosumabBMC (mg)15Total Trabecular Cortical Outer Inner Sub<strong>cortical</strong> 15 Total Trabecular Cortical Outer Inner Sub<strong>cortical</strong>9.9%*8.4%*Percent Change From Basel<strong>in</strong>e1050-56.4%*6.4%*5.5%* 5.5%* 5.4%*0% 0.1%−1.5% † −0.3%−1.7%−7.8% †1050-54.8%*4.9%*3.9%* 4.0%* 3.7%*−1.1% −1.0% −1.5% †−2.6% † −3.1% †−9.0% †-10-10-15LS Mean95% CI; *P < 0.0001 vs both basel<strong>in</strong>e <strong>and</strong> placebo; † P < 0.05 vs basel<strong>in</strong>e.-15
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