Sarah O'Connor's CV - John Innes Centre

More documents

Recommendations

Info

• Opila, R. L., Konstadinidis, K., O'Connor, S. (1997) X-ray photoelectron spectroscopic study of the reactions between metals (Cr, Ti, Al) and polymers (triazine and polyimide). Polymer Surfaces and Interfaces: Characterization, Modification and Application 179-187. • O'Connor, S. E., Imperiali, B. (1996) Modulation of protein structure by asparagine-linked glycosylation. Chem. Biol. 3, 803-812. Recent Research Grants Pending BBSRC, Enzymes of Ergot Alkaloids, 09/12 – 09/15 (under review) BBSRC, Developing Bioinformatic Strategies to Rapidly Elucidate and Exploit Plant Metabolites for Industry, 09/12 – 09/13 (under review) ERC Starting Grant, Synthetic Metabolism in Plants: Elucidating Vinblastine Biosynthesis and Implementing Strategies to Overproduce Complex Plant Metabolites, 12/12 – 12/17 (under review) EPSRC, Generation of Alkaloid Structural Diversity Using Biocatalysts, 04/12 – 04/15 (under review) Current Support BB/J009091/1 04/12 – 04/15 BBSRC (funded- awaiting confirmation of final amount of award) Towards Plant Synthetic Biology: Elucidating the Novel Enzymology of Iridoid Biosynthesis This project describes uncovering the enzymology of terpene biosynthesis. RO1-GM074820-04 (O’Connor, PI) 04/01/07 – 02/29/12 NIH $1,466,142 Early Steps in Alkaloid Biosynthesis This project describes the use of biosynthetic pathways to make new natural products by precursor directed biosynthesis. 1RC2GM092521 (Chappell, U. KY, Program Director; Della Penna, MSU; O’Connor, MIT co- Program Directors) 09/30/09 – 09/29/12 NIH $595,681 Advancing Drug Development in Medicinal Plants Using Transcriptomics and Metabolomics This multi-investigator proposal describes the transcriptional and metabolic profiling of medicinal plant species. Past Support RO1-GM074820-03S1 (O’Connor, PI) 07/15/09 – 06/30/10 NIH $106,458 Early Steps in Alkaloid Biosynthesis This award was an Administrative Supplement. RSG-07-025-01 (O’Connor, PI) 01/01/07-12/31/10 American Cancer Society $720,000 Production of Vinblastine Analogues in Madagascar Periwinkle This project described the chemoenzymatic synthesis and biological assay of anhydrovinblastine and vinblastine analogues. MCB-0719120 (O’Connor, PI) 10/01/07-09/30/10 NSF $445,856 Combinatorial Biosynthesis of New Alkaloids in Periwinkle 4
This project described transformation of new enzymes into periwinkle to generate genetically engineered plant cell cultures that make new natural products. Sloan Fellowship (O’Connor, PI) 09/16/07-09/15/09 Alfred P. Sloan Foundation $22,500 Research Fellowship This award was unrestricted. (O’Connor, PI) 05/01/07-04/30/08 David Koch Research Fund $100,000 Harnessing the Production of Anti-Cancer Agents from Plants This project described synthesis of new alkaloid biosynthesis starting materials. (O’Connor PI) 07/01/06 – 06/30/08 J. J. and E.V. Wade Fund $25,000 Directed Biosynthesis of Terpene Indole Alkaloids This project described the directed biosynthesis of terpene indole alkaloids in C. roseus (O’Connor PI) 09/01/06 – 08/31/08 Paul Cook Innovation Fund $15,000 This project described redesign of a central enzyme in alkaloid biosynthesis: implication for plant metabolic engineering. (O’Connor, PI) 09/15/05-09/14/08 Beckman Foundation $88,000 Natural Product Diversity This project outlined the development of new methods to stimulate natural product production in microbes. (O’Connor, award) Latham Family Career Development 07/01/04-06/30/07 Latham Family Endowment $60,000 This award was unrestricted. (O’Connor, PI) 07/01/04-08/31/06 Petroleum Research Fund $35,000 Characterization of Strictosidine Synthase, A Key Enzyme in Alkaloid Biosynthesis This grant described the initial characterization of strictosidine synthase. (O’Connor, PI) 12/01/03-11/30/05 Smith Family Foundation $200,000 Human Biosynthesis of Alkaloids This proposal described elucidating the function of human homologues to plant biosynthetic enzymes. (O’Connor, PI) 07/01/04 3M Innovation Fund $50,000 Early Steps of Terpene Indole Alkaloid Biosynthesis This proposal described mechanistic studies of the second enzyme of the terpene indole alkaloid pathway, strictosidine glucosidase. (O’Connor, PI) 07/01/04 Ferry Fund $50,000 Alkaloid Biosynthesis This grant supported research on mechanistic studies of strictosidine synthase. 5
Page 1 and 2: Curriculum Vitae SARAH E. O’CONNO
Page 3: • Galan, M. C., McCoy, E., O'Conn
Page 7 and 8: • Indiana University, Chemistry D

Sarah O'Connor's CV - John Innes Centre

Create successful ePaper yourself

Delete template?

Save as template?