Acute Infectious Diarrhea - Duke Pediatrics Intranet

Clinical Manifestations-EntericsEnterics (lactosenon-fermenting)Clinical Complications Antimicrobials?Non-typhiSalmonella sp.•Fever•Gastroenteritis•Endovascular disease(greatest in older patients)•< 6 mo old•Toxin/bacteremic•Moderate fecal PMN•ImmunocompromisedShigella•Watery to dysentery•Toxic megacolon•Treat all•Leukomoid reaction•Reactive arthritis (2%)•Seizures•High fecal PMN•Hemolytic-uremic syndrome(HUS)Yersinia•Fever, pain, diarrhea•Reactive arthritis•Depends on severity•Invasive ileitis, colitis•Bacteremic/Toxic•Mesentericlymphadentitis (clinicallylike appy)•+/- PMNsC. jejuni •Dysentery-acute colitis•Fecal PMN present•Reactive arthritis, 1%•Guillain-Barre•Treat severe cases