BPHM4142 Molecular Pharmacology Year 3/4 (6 credits)This course examines the molecular basis <strong>of</strong> drug interaction with the cell and explores how cuttingedge biotechnology and biomedical research can advance pharmacological knowledge, henceimproving students’ understanding <strong>of</strong> how drugs work. <strong>The</strong> structure <strong>of</strong> the course is divided into 4main themes: (i) advanced knowledge on gene, protein and cells as drug targets; (ii) cutting-edgetechnologies in pharmacology and drug discovery; (iii) molecular pharmacology <strong>of</strong> receptors,channels and enzymes; (iv) signal transduction and modulation. A special topic will be selectedeach year to review updated drug development and news in a particular field.Prerequisite: Pass in BBMS2005 Basic PharmacologyAssessment: 30% assignment; 70% examination.BPHM4147 Toxicology and Drug Abuse Year 3/4 (6 credits)This course provides students with an understanding <strong>of</strong> the toxicological problems encountered inclinical practice, drug development and medical research. Introduction to the biotransformationand toxicity <strong>of</strong> drugs, carcinogenicity, drug addiction and withdrawal syndrome; physiological,pharmacological and sociological consequences <strong>of</strong> drug abuse; treatment regimens <strong>of</strong> drug abuse.Prerequisite: Pass in BBMS3014 Advanced PharmacologyAssessment: 30% continuous assessment; 70% examination.BBMS4002 Pharmaceutical Drug Development Year 4 (6 credits)This course is aimed to provide a broad overview <strong>of</strong> the process and the current trends <strong>of</strong>pharmaceutical drug development, and the challenges in drug delivery including small molecules,biologics and therapeutic nucleic acids. Novel drug delivery systems, the process <strong>of</strong> clinical trials aswell as the development <strong>of</strong> nanomedicine will be discussed. <strong>The</strong> course prepares students forpossible future employment in the pharmaceutical industry.Prerequisite: Pass in BBMS2005 Basic PharmacologyAssessment: 30% continuous assessment; 70% examination.Elective CoursesBBMS3010 Emerging Infections Year 3/4 (6 credits)This course will introduce students to the comparative human/animal infections and diseases withemphasis on zoonotic viral infections. <strong>The</strong> course investigates the pathogenesis <strong>of</strong> microbes <strong>of</strong> recentconcern, focusing on the particularly innovative molecular processes these organisms use to ensuretheir success in surviving and multiplying in the human host. It also provides new insights into thephylogenetic relationships between microorganisms based on molecular systematics as well as intothe latest issues <strong>of</strong> pathogenesis, pandemic, prevention and eradication.Prerequisite: Pass in BBMS3005 Infection and Immunity or BBMS3001 Medical MicrobiologyAssessment: 30% continuous assessment; 70% examination.BBMS3011 Molecular Neuroscience Year 3/4 (6 credits)This course provides an interdisciplinary introduction to fundamental aspects <strong>of</strong> the structure andfunction <strong>of</strong> the nervous system. <strong>The</strong> topics to be covered include the properties <strong>of</strong> nerve and glialcells, the ionic and molecular basis <strong>of</strong> neural excitability, synaptic transmission and plasticity, signaltransduction, as well as neural network for brain functions, such as perception, motor control,cognition, dementia, and emotional disturbance.Prerequisite: Pass in BBMS3002 Molecular Biology <strong>of</strong> the CellAssessment: 30% continuous assessment; 70% examination.
BBMS3012 Stem Cell & Regenerative Medicine Year 3/4 (6 credits)Numerous human diseases resulting from the loss or malfunction <strong>of</strong> highly specialized cell types arecurrently incurable due to lack <strong>of</strong> capacity to regenerate due to diseases, traumas or aging. Recentadvances in stem cell research have enabled clinicians and researchers to pursue for the first timerevolutionary treatment paradigms based on regenerating human cells. In this course, acomprehensive introduction <strong>of</strong> the biology <strong>of</strong> stem cells, tissue engineering, industrial and clinicalapplications, bioethics, historical and political developments will be given. Upon completion,students should have a global perspective <strong>of</strong> the emerging field <strong>of</strong> Stem Cell & RegenerativeMedicine that bounds to revolutionize how medicine will be practiced.Prerequisite: Pass in BBMS3002 Molecular Biology <strong>of</strong> the CellAssessment: 30% continuous assessment; 70% examination.BBMS3013 Clinical Trial Strategies Year 3/4 (6 credits)This course will discuss the history <strong>of</strong> clinical trials, as well as the history <strong>of</strong> research ethics inclinical trials. <strong>The</strong> main features <strong>of</strong> clinical trials will be highlighted including trial guidelines,research ethics practice; responsibility and liability; quality assurance, audits and Good ClinicalPractice (GCP); documentation and study monitoring. Clinical data management; and protocoldevelopment will also be featured.Prerequisite: Pass in BIOL2102 Biostatistics and BBMS2002 Evidence-based Practice and PublicHealthAssessment: 30% continuous assessment; 70% examination.BBMS3017Disease IIPhysiological Basis <strong>of</strong> Health andYear 3/4 (6 credits)This course examines the concepts related to the physiological function <strong>of</strong> the human body and thepathophysiological processes under disease conditions. <strong>The</strong> focus throughout the course will be onphysiology and pathophysiology <strong>of</strong> cellular and molecular functions, haematology, cardiovascular,gastrointestinal, respiratory, nervous, musculoskeletal, endocrine and reproductive systems. <strong>The</strong>course serves as an advance level <strong>of</strong> understanding <strong>of</strong> physiological functions <strong>of</strong> the human body innormal and disease states.Prerequisite: Pass in BBMS2006 Physiological Basis <strong>of</strong> Health and Disease IAssessment: 60% continuous assessment; 40% examination.