Approach to Rash in a Patient with HIV
Approach to Rash in a Patient with HIV
Approach to Rash in a Patient with HIV
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Abacavir HSR• Most signs/symp<strong>to</strong>ms resolve ≤48 hafter s<strong>to</strong>pp<strong>in</strong>g ABC• Re-challeng<strong>in</strong>g patients <strong>with</strong> prior ABCHSR, results <strong>in</strong> life-threaten<strong>in</strong>g allergicreaction <strong>with</strong><strong>in</strong> hours• Prior <strong>to</strong> ABC use, patient should bescreened for HLA-B*5701 allele• <strong>Patient</strong>s hav<strong>in</strong>g HLA-B*5701 alleleshould be listed as allergic <strong>to</strong> ABC
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