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Advances in Lung Transplantation - Royal Perth Hospital

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hange <strong>in</strong> FEV1 (% pred) after switch from CyA to Tacrolimus<br />

FEV1% predicted<br />

90<br />

80<br />

70<br />

60<br />

50<br />

40<br />

30<br />

20<br />

10<br />

0<br />

FEV1( % pred) - Time course<br />

Mean monthly loss <strong>in</strong><br />

FEV1% = 2.65%<br />

Best value 6 mo. 3 mo. switch 3 mo. 6 mo. 12 mo.<br />

OB RAR Total<br />

Mean monthly loss <strong>in</strong><br />

FEV1% = 1.0%<br />

arahrudi K, Estenne M, Corris P, Niedermayer J, Knoop C, Glanville AR, Chapparo C et al.<br />

nternational experience with conversion from cyclospor<strong>in</strong>e to tacrolimus for acute and chronic lung allograft rejection.<br />

Thorac Cardiovasc Surg, 2004; 127:1126-1132.

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