Introduction to X-ray Crystallography

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Experimental Determination of Atomic Resolution StructuresX‐rayNMRX‐raysDiffractionPatternRFRFResonanceH0‣Direct detection ofatom positions‣Crystals‣Indirect detection ofH-H distances‣In solutionOther methods for determining protein structures:‐EM, Cryo‐EM, ESR/Fluorescence
Yufeng Zhouhttp://www.noble.org/PlantBio/Wang/crystallography.html
Page 2 and 3: Contributions to this lecture:Yong
Page 6 and 7: Why Crystals?Yong Xiong
Page 8 and 9: Data CollectionCrystallography 101
Page 10 and 11: Image of diffraction
Page 12 and 13: Most famous X‐ray diffraction pat
Page 14 and 15: The information we get from a singl
Page 16 and 17: Electron density mapBuilding a stru
Page 19: Yale's Thomas Steitz shared 2009 No
Page 22: Tools for Viewing Structures• Jmo

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