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PowerPoint-Aaron Cowieson - The Poultry Federation

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A note on phytate› Differential scanning calorimetry and vapour pressure osmometry used toexplore the interaction between protein and phytate› Phytate DOES bind directly to protein provided that the pH is below the pIof the protein› Thus, in the gastric phase of digestion phytate crosslinks protein, droppingout of solution› In the small intestine phytate acts indirectly as a Hoffmeister anion› Importantly, ANIONS displace phytate from the protein surface thus thoughmuch has been made of the putative interacting effects of phytate and Nait may be Cl and other anions that are responsibleBye, J.W., <strong>Cowieson</strong>, N.P., Scwarz, R.R., <strong>Cowieson</strong>, A.J., Selle, P.H. & Falconer, R.J. (2012) <strong>The</strong> dual effects ofsodium phytate on the structural stability and solubility of proteins. Journal of Biological Chemistry, Under Review.26

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