cough-variant asthma - Kelkar - World Allergy Organization

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Natural history of NAEB• In one study of 32 patients, one patienthad complete resolution, 21 (66%) hadpersistent symptoms/inflammation, 3(9%) developed asthma, 5 (16%)developed fixed airflow obstruction• Causal association between NAEB andCOPD- ??Berry MA, et al. Clin Exp Allergy2005;35(5):598-601
Immunopathology• Mast cells are localized and activated inmore superficial airway epithelium innonasthmatic eosinophilic bronchitis,whereas in asthma they lie deeper inclose association with the airwaysmooth muscle
Page 1 and 2: Cough-variant AsthmaPramod Kelkar,
Page 4 and 5: Eosinophilic bronchitis• NAEB- No
Page 6 and 7: Exhaled Nitric Oxide/eNO• Levels
Page 10 and 11: Recurrent Cough• What is the like
Page 12 and 13: Cough in an asthmatic child• Coug
Page 14 and 15: PatientDeaths(%)Pediatric Asthma De
Page 16 and 17: Key New Concepts of AsthmaManagemen
Page 18 and 19: Asthma Severity and Control: Risk D
Page 20 and 21: Asthma Severity: 5 to 11 Years*Comp
Page 22 and 23: Assessing Asthma Control inChildren
Page 24 and 25: Key Changes in AssessingAsthma Cont
Page 26 and 27: Wheezing Children: Asthma or Not?
Page 28 and 29: Early Aeroallergen Sensitization in
Page 30 and 31: Effect of Inhaled Budesonideon Infl
Page 32 and 33: Many Patients Incorrectly Perceive
Page 35 and 36: Exploring Reasons for Failureof Ast
Page 37 and 38: Asthma Action Plan until __________
Page 39 and 40: Key Questions• Are Peak Flow Mete
Page 41 and 42: Can you outgrow asthma?• 10-39% r
Page 43 and 44: Don’t forget to address• Enviro
Page 45 and 46: Stepwise Approach for Managing Asth
Page 47 and 48: Inhaled Steroids Target MultipleInf
Page 49 and 50: The Risk of Asthma in Wheezing Chil
Page 51 and 52: Follow-Up• Visits every 2-6 weeks
Page 53 and 54: What can lead to “difficult-to-co
Page 55 and 56: Can diet affect respiratory system?
Page 57 and 58: Bibliography(1) Ramanuja S, Kelkar
Page 59:
Thank you!Pramod Kelkar, MDFounder,
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cough-variant asthma - Kelkar - World Allergy Organization

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