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1 Continental J. Pharmacology and Toxicology ... - Wilolud Journals

1 Continental J. Pharmacology and Toxicology ... - Wilolud Journals

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Aftab Alam et al: <strong>Continental</strong> J. <strong>Pharmacology</strong> <strong>and</strong> <strong>Toxicology</strong> Research 2: 19 - 26, 2008.CONCLUSIONThe clinical study of formulation indicates HT-gel (1gram) was active for 12-hours in maintaining oral hygienecondition while CH X (Std-10ml) was active for 5-8 hours <strong>and</strong> Herbal mouth rinse (10ml) was active for 2-5 hour.ACKNOWLEDGEMENTS.We would like to thank Prof. B.G Shivan<strong>and</strong>a, Principal Al-Ammen College of Pharmacy, Dr. Salma KhanamHOD, Dept. of Pharmacognosy Al-Ammen College of Pharmacy Bangalore Karnataka India, for providing suchgood environment for this projects. Dr. Jaye Prasad N Shethy Principal Gov. Dental College Bangalore KarnatakaIndia, provided us with additional data for his dual-buffering system <strong>and</strong> also provide facilities for achievement oftarget.Table –1: Percentage differences of S. mutans after 0h, 2h, 5h <strong>and</strong> 8h use of formulationsGroup Timeintervals4(n%)3(n%)HMR 0 hour - 1(10%)2(n%)5(50%)1(n%)3(30%)0(n%)1(10%)Total(n%)10(100%)2hour - - 2(20%)6(60%)2(20%)10(100%)5hour - - - 1(10%)9(90%)8 hour - - - - 10(100%)CH x Rinse 0 hour - 45 10(40%) (50%) (10%) (0.00%)10(100%)10(100%)10(100%)2 hour - 1(10%)5(10%)3(30%)1(10%)10(100%)5 hour - - 3(30%)4(40%)8 hour - - - 2(20%)3(30%)8(80%)10(100%)10(100%)HTG 0 hour 2(20%)5(50%)3(30%)0(0.00%)0(0.00%)10(100%)2 hour - 4(40%)5(50%)1(10%)0(0.00%)10(100%)5 hour - - 5(50%)8 hour - - 1(10%)4(40%)6(60%)1(10%)3(30%)10(100%)10(100%)CH x = Chlorhexidine gluconate (0.2%), HMR= Herbal mouth rinse, HTG= Herbal toothpaste gel.4

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