Comparative Genome Analysis

Neutrality, bigger than even most“neutralists” may have thoughtlikely.• “Surprisingly, i many functional elements areseemingly unconstrained acrossmammalian evolution. This suggests thepossibility of a large pool of neutralelements that are biochemically active butprovide no specific benefit to the organism.This pool may serve as a 'warehouse' fornatural selection, ,potentially acting as thesource of lineage-specific elements andfunctionally conserved but non-orthologouselements between species.”