Biosensor for Point-of-care Testing
Biosensor for Point-of-care Testing
Biosensor for Point-of-care Testing
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Enhancement Assay <strong>for</strong> Immunochromatographic test strip<br />
antigen<br />
Nanogold labeled antibody<br />
Apply sample solution to a<br />
conjugation pad<br />
Conjugation pad<br />
Test line<br />
Control line<br />
Antigens react with nanogold- Antigen-antibody<br />
labeled antibodies and<br />
complex<br />
complex flow to capture antibodies<br />
Capture antibody on test line<br />
Antibody <strong>for</strong> control line<br />
(PCT/JP2006/323617)<br />
flow<br />
Absorption pad<br />
Normal strip Enhancer-based strip<br />
The complex <strong>of</strong> antigen and nanogold labeled antibodies accumulated and a higher amount <strong>of</strong><br />
gold nanoparticles in close proximity were brought in the enhanced test strip. As a result, higher<br />
Intensity <strong>of</strong> the localized surface plasmon resonance absorbance <strong>of</strong> the nanogold particles are<br />
able to obtain and a distinct red color can be easily observed.
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