LESSON 4 Using Bioinformatics to Analyze Protein Sequences

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LESSON 4Bioinformatics & Proteins: Slide #1333. Show Slide #14. Ask students to help you translate the DNA in the firstreading frame. Each pink bar corresponds to a single codon in the first readingframe. This is often referred to as the +1 reading frame.• Codon 1 = CCG Ú Proline (P).• Codon 2 = ATG Ú Methionine (M).• Codon 3 = TCA Ú Serine (S).• Codon 4 = TAA Ú STOP.Bioinformatics & Proteins: Slide #14Using Bioinformatics: Genetic Research34. Show Slide #15, which shows translation from the first reading frame.35. Next, show Slide #16, which repeats the exercise with the second readingframe (purple bars). This is called the +2 reading frame.• Codon 1 = CGA Ú Arginine (R).• Codon 2 = TGT Ú Cysteine (C).• Codon 3 = CAT Ú Histidine (H).• Codon 4 = AAG Ú Lysine (K).132©Northwest Association for Biomedical Research—Updated October 2012
LESSON 4Bioinformatics & Proteins: Slide #15Bioinformatics & Proteins: Slide #16Bioinformatics & Proteins: Slide #17Lesson 4 – Using Bioinformatics to Analyze Protein Sequences133©Northwest Association for Biomedical Research—Updated October 2012
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LESSON 4 Using Bioinformatics to Analyze Protein Sequences

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