Spontaneous Pneumothorax: Why Anger Management is Important

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Alpha-1 Antitrypsin Major plasma serine protease inhibitorcbms.mq.edu.au Lack of exposes lung tissue to uncontrolled proteolyticattack from neutrophil elastase, culminating in alveolardestruction A1AT deficiency is one of the most common autosomalcodominant inherited disorder in Caucasians In people, specific genotypes are associated with serumlevels which are correlated with severity of emphysema Smoking and A1AT deficiency increase risk andprogression of emphysemaFregonese L et al. Alpha-1 antitrypsin Null mutations and severity of emphysema. Resp Med 2008:102;876-884.
ObjectivesObjective one Perform immunohistochemistry on lung samples fromdogs diagnosed with spontaneous pneumothoraxHypothesisQwickstep.com Lung tissue from dogs diagnosed with spontaneouspneumothorax would have abnormal stainingpattern for folliculin and/or alpha-1 antitrypsin
Page 1: Paragonvet.comImaging.consult.comSt
Page 4: Radiographic Findingsvetstreamcanis
Page 7: Treatment RecommendationsThoracocen
Page 13 and 14: Materials and Methods Two portions
Page 15 and 16: Candidate Gene Analyses Folliculin
Page 17 and 18: Recurrence, 4/15= 27% 5.8 yo, M/N,
Page 19 and 20: Alpha 1 Antitrypsin IHCa1at sub-ple
Page 21 and 22: Conclusions Focal to multifocal or
Page 23 and 24: Recommendations for SP Surgery vs.

Spontaneous Pneumothorax: Why Anger Management is Important

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