Chapter 15 - People

A Sample Case 373Repeating E&R loop: focus = FUNGAL-MENINGITIStask METARULE399 succeeded.Enter PH loop: focus = CRYPTOCOCCUSA cancer patient is at some risk of getting cryptococcal meningitis. Rather than asking directly if the patienthas cancer, the program models an expert's efficient casting of a wider net by asking a more generalquestion. Specifically, there are "screening rules," that lead it to determine first if the patient isimmunosuppressed (RULE39S) and then compromised (RULE343). This is the only form of backwardchaining that occurs in NEOMYCIN. 2task METARULE431 succeeded.--[0] Findout: LEUKEMIA--[1] Findout: IMMUNOSUPPRESSEDTrying RULE343;8) Is Mike a compromised host (e.g. alcoholic, sickle-cell-disease,immunosuppressed)?** YESRULE343 failed due to clause 1If the patient were not compromised, the program could have concluded that he is not immunosuppressed(RULE343). Now it is unsure and must ask direct/yo If the patient is not immunosuppressed, the program willknow that he does not have leukemia (RULE39S). The answer of LEUKEMIA below impliesimmunosuppressed, so RULE39S fails, and the original goal is determined.--[1] Finished: IMMUNOSUPPRESSED9) Is Mike immunosuppressed (e.g. corticosteroid therapy, cytotoxic drugtherapy, radiation therapy, leukemia)?** LEUKEMIAI will assume that leukemia is one of the diagnoses of MikeRULE395 failed due to clause 1--[0] Finished: LEUKEMIATrying evidence rules: LEUKEMIA -+ CRYPTOCOCCUSTrying RULE056; succeeded.Conclude: FUNGAL-MENINGITIS is CRYPTOCOCCUS (.3)Repeating E&R loop: focus = CRYPTOCOCCUStask METARULE401 succeeded.Attention turns to a sibling. Again, the "enabling step" is asked about first . ...Enter PH loop: focus = COCCIDIOIDEStask METARULE411 succeeded.10) Has the patient ever been to a cocci-endemic area?** NOTrying evidence rules: COCCI-ENDEMIC -+ COCCIDIOIDESRULE570 failed due to clause 1RULE287 failed due to clause 1observed STOP-PURSUING METARULE408Repeating E&R loop: focus = COCCIDIOIDESRepeating EHS loop: focus = COCCIDIOIDEStask METARULE430 succeeded.2Ed. notf: A later version of NEOMYCIN accomplishes this form of inference by meta-rules.