HumanBioMonitoring-Schoeters - BioDetection Systems

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A brief introduction to HBM• Environmental health sciencesContaminantsin theEnvironmentHumanBiomonitoringPossibleadversehealth effectsBiomarkersof exposureBiomarkersof effectExposureDoseResponse
Aim of HBM programs– Find out if there are traces of environmental contaminantsdetectable in human tissues (time trends);– Detect whether these traces are uniformly distributed inspace, or whether there are differences among differentareas (spatial trends);– Determine which factors may be able to explain theobserved variations in chemical concentrations (exposure);– Determine whether there is a relation between the exposureto these pollutants and the occurrence of health effects(effect);– Evaluate and, if necessary, adjust environment and healthpolicy (risk management).
Page 2 and 3: Outline• An introduction to human
Page 4 and 5: The causal chain:from exposure to e
Page 6 and 7: A brief introduction to HBMspecific
Page 10 and 11: Evaluating time trendsMean lipid-ad
Page 12 and 13: Relation with health effects
Page 14 and 15: o evaluate the efficacity of policy
Page 16 and 17: European initiatives humanbiomonito
Page 18 and 19: The future: The EU Pilot ProjectESB
Page 20 and 21: 2 Main types of HBM activities- SUR
Page 22 and 23: wo protocolsASilicacolumnHexane/DEE
Page 24 and 25: Breast milk monitoringblicationCoun
Page 26 and 27: HBM in FlandersFlanders(1998)EU(199
Page 28 and 29: Effect of gender:Marker PCBs (ng/ g
Page 30 and 31: Determinants of CALUX TEQin adolesc
Page 32 and 33: Correlation between CaluxTEQ and to
Page 34 and 35: Study areas:8 study areas in Flande
Page 36 and 37: FLEHS: newborns cord blood (2002-20
Page 38 and 39: HBM in Flanders• Some results-Ris
Page 40 and 41: PitfallsComparison between differen

HumanBioMonitoring-Schoeters - BioDetection Systems

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