Annual report 2008/09 - Human Fertilisation & Embryology Authority

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Contents31 Introduction 42 Outcomes of 2007/8 horizon scanning process 52.1 Trophectoderm biopsy 52.2 Use of tripronucleated (3PN) embryos 62.3 Microcytoplast cryopreservation of oocytes 82.4 Gene transfer into embryos 92.5 Gene transfer into male germ lines 112.6 Cryopreservation of immature testicular tissue and spermatogonial cells 122.7 Alternative methods of obtaining embryonic or embryonic-like stem cells 132.8 In vitro derived gametes 163 Issues identified in the 2008/9 horizon scanning process 184 References 29Human Fertilisation & Embryology AuthorityScientific Horizon Scanning at the HFEA
4Section 1IntroductionHorizon scanning is an early-warning system whichallows the HFEA to consider the legal, ethical andregulatory implications of any techniques thatresearchers or clinicians may wish to use in the futurein HFEA-licensed research or treatment. The Authoritycan then be prepared with information to make adecision on the potential licensing of techniques, orhave guidance in place to ensure that new treatmentsare carried out safely and appropriately. The HFEAcan also ensure that patients and the wider public aresuitably informed.This year the horizon scanning process has also beenused to gather information on techniques which theHuman Fertilisation and Embryology Act 2008 willpermit from October 2009 (eg, genetic modificationof embryos for research).Relevant research is identified throughout the yearby reviewing journals and attending conferences.Common themes are then identified and researchedfurther. Views are sought from experts, such asmembers of the HFEA’s Horizon Scanning Panel.This report summarises the HFEA’s horizon scanningactivity for 2008/9, and the outcomes from 2007/8,to inform interested researchers, clinicians, membersof the public and other stakeholders by outlining thehigh priority issues considered throughout 2008, anyresulting actions and the issues identified forconsideration in 2009. If centres wish to carry out anyof the techniques described in this report they wouldneed to inform the Authority or apply for a licenceand, where necessary, further consultation will becarried out. A licence committee of the Authoritywould consider the details of each individualapplication before the technique could be used.Human Fertilisation & Embryology AuthorityScientific Horizon Scanning at the HFEA
Page 1: ScientificHorizonScanningat the HFE
Page 6 and 7: Section 2Outcomes of 2007/8horizon
Page 18 and 19: Section 3Issues identified in the 2
Page 28 and 29: Section 4References291Dokras A et a

Annual report 2008/09 - Human Fertilisation & Embryology Authority

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