Chemotherapy Plus Radiotherapy Versus Radiotherapy Alone For ...

Accrual and Other Features• 299 patients accrued at 76 institutions over 8 years• Eight randomized cases were ineligible (four / arm)• 148 randomized to PCV+RT; 143 to RT alone arm• Arms balanced for clinical and pathological factors• 46% of patients tolerated 4 full-dose cycles of I-PCV• Two deaths were attributable to I-PCV neutropenia• 79% in RT arm got “PCV” at progression (p