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Evaluation of Antioxidant Activities of Bergenia ciliata Rhizome

Evaluation of Antioxidant Activities of Bergenia ciliata Rhizome

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47Rajkumar et al, Rec. Nat. Prod. (2010) 4:1 38-48AcknowledgementThe authors gratefully acknowledge Mr. C. Sathyanarayanan, Arya Vaidya Pharmacy(Coimbatore) Ltd., Kanjikode, Palakkad, India for his active support. The authors also thank themanagement <strong>of</strong> VIT University, Vellore for providing the necessary facilities for this research.References:[1] B. Halliwell, J.M.C. Gutteridge and C.E. Cross (1992). Free radicals, antioxidants and human disease:where are we now? J Lab Clin Med. 119, 598-620.[2] D.J. Lefer and D.N. Grander (2000). Oxidative stress and cardiac disease. Am J Med. 109, 315-323.[3] N. Ito, M. Hiroze, G. Fukushima, H. Tauda, T. Shira and M. Tatematsu (1986). Studies on antioxidant;their carcinogenic and modifying effects on chemical carcinogensis. Food Chem Toxicol. 24, 1071-1081.[4] Y.F. Sasaki, S. Kawaguchi, A. Kamaya, M. Ohshita, K. Kabasawa, K. Iwama, K. Taniguchi and S. Tsuda(2002). The comet assay with 8 mouse organs: results with 39 currently used food additives. Mutat Res-Gen Tox En. 519, 103-119.[5] S. Sinha, T. Murugesan, K. Maiti, J.R. Gayen, B. Pal, M. Pal and B.P. Saha (2001). Antibacterial activity<strong>of</strong> <strong>Bergenia</strong> <strong>ciliata</strong> rhizome. Fitoterapia 72(5), 550-552.[6] S. Sinha, T. Murugesan, M. Pal and B.P Saha (2001). <strong>Evaluation</strong> <strong>of</strong> anti-tussive activity <strong>of</strong> <strong>Bergenia</strong><strong>ciliata</strong> Sternb. rhizome extract in mice. Phytomedicine 8(4), 298-301.[7] M. Islam, I. Azhar, U. Khan, M. Aslam, A. Ahmad and Shahbuddin (2002). Bioactivity evaluation <strong>of</strong><strong>Bergenia</strong> <strong>ciliata</strong>. Pak J Pharm Sci. 15(1), 15-33.[8] E. Lister and P. Wilson (2001). Measurement <strong>of</strong> total phenolics and ABTS assay for antioxidant activity(personal communication). Crop Research Institute, Lincoln, New Zealand.[9] A. Yildirim, A. Mavi and A.A. Kara (2001). Determination <strong>of</strong> antioxidant and antimicrobial activities <strong>of</strong>Rumes crispus L. extracts. J Agr. Food Chem. 49, 4083-4089.[10] M.S. Blois (1958). <strong>Antioxidant</strong> determinations by the use <strong>of</strong> stable free radical. Nature 81, 1199-2000.[11] B. Halliwell and J.M.C. Gutteridge (1999). Free radicals in biology and medicine. 3 rd edition, OxfordUniversity Press, Oxford, UK.[12] NIH (1985). Principles <strong>of</strong> laboratory care. NIH publication 85-23, NIH, Bethesda, MD.[13] S.M. Klein, G. Cohen and A.I. Cederbaum (1981). Production <strong>of</strong> formaldehyde during metabolism <strong>of</strong>dimethyl sulphoxide by hydroxyl radical generating system. Biochem. 20, 6006-6012.[14] A. Russo, A.A Izzo, V. Cardile, F. Borrelli and A. Vanella (2001). Indian medicinal plants as antiradicalsand DNA cleavage protector. Phytomedicine 8 (2), 125-132.[15] Y.S. Velioglu, G. Mazza, L. Gao and B.P. Oomah (1998). <strong>Antioxidant</strong> activity and total polyphenolics inselected fruits, vegetables, and grain products. J Agr Food Chem. 46, 4113-4117.[16] Y. Choi, H.S. Jeong and J. Lee (2007). <strong>Antioxidant</strong> activity <strong>of</strong> methanolic extracts from some grainsconsumed in Korea. Food chem. 103, 130-138.[17] S. Meir, J. Kanner, B. Akiri and S.P. Hadas (1995). Determination and involvement <strong>of</strong> aqueous reducingcompounds in oxidative defense systems <strong>of</strong> various senescing leaves. J Agr Food Chem. 43, 1813-1815.[18] P. Siddhuraju, P.S. Mohan and K. Becker (2002). Studies on the antioxidant activity <strong>of</strong> Indian Laburnum(Cassia fistula L.): a preliminary assessment <strong>of</strong> crude extracts from stem bark, leaves, flowers and fruitpulp. Food Chem. 79, 61-67.[19] G.C. Yen, P.D. Duh and C.L. Tsai (1993). Relationship between antioxidant activity and maturity <strong>of</strong>peanut hulls. J Agr Food Chem. 41, 67-70.[20] J. Javanmardi, C. Stushn<strong>of</strong>f, E. Locke and J.M. Vivanco (2003). <strong>Antioxidant</strong> activity and total phenoliccontent <strong>of</strong> Iranian Ocimum accessions. Food Chem. 83, 547-550.[21] M.S Bagul, M.N Ravishankara, H. Padh and M. Rajani, (2003). Phytochemical evaluation and free radicalscavenging properties <strong>of</strong> rhizome <strong>of</strong> <strong>Bergenia</strong> <strong>ciliata</strong> (Haw) Sternb. J Nat Rem. 3, 83-89.[22] B. Halliwell, R. Aeschbach, J. Loliger and O.I. Aruoma (1995). The characterization <strong>of</strong> antioxidants.Food Chem Toxicol. 33, 601-617.[23] L.J. Marnett (1999). Lipid peroxidation-DNA damage by malondialdehyde. Mutat Res. 424, 83-95.[24] P. Hochestein and A.S. Atallah (1988). The nature <strong>of</strong> oxidant and antioxidant systems in the inhibition <strong>of</strong>mutation and cancer. Mutat Res. 202, 363-375.

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