CAGE PROCESSING in Animal Facilities - GV-SOLAS

4.4.2.2 Design of bottle fillers ................................................................................................................ 274.4.2.3 Bottle filling systems – advantages / disadvantages ................................................................. 284.5 Steam sterilisation ..................................................................................................................... 284.5.1 Requirements of steam sterilisers ............................................................................................. 284.5.1.1 Products and materials ............................................................................................................. 284.5.1.2 Devices and procedures ........................................................................................................... 294.5.1.3 Dimensions ............................................................................................................................... 304.5.1.4 Technical components ............................................................................................................... 304.5.2 Special requirements on the process validation ........................................................................ 304.6 Reduction of microorganisms on heat-sensitive items by means of hydrogen peroxide(H 2O 2)/peracetic acid (PAA) ....................................................................................................... 314.6.1 Material lock .............................................................................................................................. 314.6.2 Requirements of processing procedures by means of H 2O 2..................................................... 324.6.2.1 Basic lock types for H 2O 2gassing ............................................................................................. 324.6.2.2 Constructional requirements ..................................................................................................... 334.6.2.2.1 Mechanical structure ................................................................................................................ 334.6.2.2.2 Procedural components ............................................................................................................ 334.6.2.2.3 Electrical structure ..................................................................................................................... 334.6.2.3 Processual requirements .......................................................................................................... 344.6.2.4 Processual documentation ........................................................................................................ 354.6.3 Requirements of processing procedures by means of peracetic acid ....................................... 354.6.3.1 Constructional requirements ..................................................................................................... 364.6.3.1.1 Mechanical structure ................................................................................................................. 364.6.3.1.2 Procedural components ............................................................................................................ 364.6.3.1.3 Electrical structure ..................................................................................................................... 364.6.3.2 Processual requirements .......................................................................................................... 374.6.3.3 Processual documentation ........................................................................................................ 375 Requirements of facility construction ................................................................................... 375.1 Distribution of responsibilities .................................................................................................... 375.2 Requirements of utilities and utility systems ............................................................................. 375.2.1 Water, softened water, and demineralised water ...................................................................... 375.2.2 Steam ........................................................................................................................................ 385.2.2.1 Heating steam ........................................................................................................................... 395.2.2.2 Clean steam .............................................................................................................................. 395.2.2.3 Requirements of heating steam and clean steam ..................................................................... 405.2.3 Condensate ............................................................................................................................... 405.2.4 Compressed air ......................................................................................................................... 405.2.5 Electricity ................................................................................................................................... 405.2.6 Wastewater ............................................................................................................................... 415.2.7 Process exhaust air ................................................................................................................... 415.2.8 Heat dissipation ......................................................................................................................... 415.3 Constructional dimensions, load-carrying capacity, and pit ...................................................... 415.4 Maintenance access and service room ..................................................................................... 425.5 Dispensing station for process chemicals ................................................................................. 425.6 Installation data and consumption data ..................................................................................... 436 Operation and use ................................................................................................................... 436.1 Influence of planning on operation ............................................................................................ 436.2 Start up of operation .................................................................................................................. 456.3 Handover ................................................................................................................................... 456.4 Operating staff ........................................................................................................................... 456.5 Machine log ............................................................................................................................... 456.6 Operator guide .......................................................................................................................... 456.7 Standard operating procedure (SOP) ....................................................................................... 456.8 Setting the procedural parameters ............................................................................................ 456.9 Routine checks and measures .................................................................................................. 476.10 Check of washing, drying, and steam sterilisation result .......................................................... 476.11 Maintenance measures ............................................................................................................. 477 Performance evaluation checks for washing systems ........................................................ 474Cage Processing in Animal Facilities · 4th issue · 2013