06.08.2015 Views

Probe-Level Analysis of Affymetrix GeneChip Microarray Data

Clemson version - Ben Bolstad

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Genes• The human genome is distributed along 23 pairs <strong>of</strong>chromosomes.– 22 autosomal pairs;– the sex chromosome pair, XX for females and XYfor males.• In each pair, one chromosome is paternallyinherited, the other maternally inherited.• Chromosomes are made <strong>of</strong> compressed andentwined DNA.• A (protein-coding) gene is a segment <strong>of</strong>chromosomal DNA that directs the synthesis <strong>of</strong> aprotein.

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