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Determining the tDCS dose Electrode Montage and Brain Targeting

Boston_tDCScourse_2013 - Neural Engineering Group

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Dose design for Transcranial Direct Current StimulationABCDEThe focality of <strong>tDCS</strong> can be increased using “High-Definition”electrode arrays. Models can be used to design <strong>the</strong>rapies suchas 4x1 HD-<strong>tDCS</strong>. Datta et al. <strong>Brain</strong> Stim 2009Focal HD-<strong>tDCS</strong> produces distinct neuromodulation <strong>the</strong>nconventional pad <strong>tDCS</strong>. Kuo et al. <strong>Brain</strong> Stim 2013Validation: HD-<strong>tDCS</strong> produces focal current flow. Anatomicalvariability is important for <strong>tDCS</strong> (as for TMS) <strong>and</strong> can be controlledwith computational models. Edwards et al. Neuroimage 2013Anatomical variability can change magnitude <strong>and</strong> location of peakcurrent. 4x1 HD-<strong>tDCS</strong> magnitude more sensitive, but location isrobust across individuals. Truong Neuroimage Clinical 2013Anatomical variability aggravated at extremes of age. 4x1 HD<strong>tDCS</strong>features same. Kessler PLoS One 2013

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