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Emerging Medicinal Uses of Hops

Emerging Medicinal Uses of Hops - USA Hops

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MENOHOP: CLINICAL TRIAL 4Analysis <strong>of</strong> relative 8-PN concentrations in urine(8-PN/(IX+8-PN))100Relative levels<strong>of</strong> 8-PN in urineapparently notaffected byintake <strong>of</strong> otherphytoestrogens8-prenylnaringenin (%)908070605040302010r= 0.277; P< 0.001The relative levels <strong>of</strong> 8-PN inurine appear to be low incomparison with findings fromfecal incubations!But original ratio is 6%!Thus, ratio in urine issignificantly affected.Furthermore, this may reflectthe different pharmacokineticbehaviour <strong>of</strong> IX vs 8-PN.01 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20HOPMIXAmerican Hop Convention 2009 and Hop Research Council Winter Meeting, 29 January 2009

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