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MONDAY, SEPTEMBER 28<br />

7:00 AM- 8:15 AM<br />

Potomac C<br />

Clinical Fundamentals II: FAQ’s About<br />

Heart Failure Drug Therapy<br />

Moderators: Mariell Jessup, Philadelphia, PA<br />

Jo Ellen Rodgers, Chapel Hill, NC<br />

Discussion Panel:<br />

John Chin, Sacramento, CA<br />

Daniel Dries, Philadelphia, PA<br />

Gerasimos Filippatos, Athens, Greece<br />

Heather Ross, Toronto, ON, Canada<br />

Mark Semigran, Boston, MA<br />

7:00 Case 1 & FAQs:<br />

55-year-old male with HTN, diabetes, and history of childhood<br />

asthma is admitted with new onset heart failure, LVEF<br />

20%. He has non-critical CAD and is stable after 2 days of<br />

IV diuretic. His BP is now 140/90 mmHg, and his heart rate<br />

is 70 bpm. Renal function is normal.<br />

Which ACE-inhibitor would you start?<br />

When do you start the beta-blocker?<br />

When do you start the MRA?<br />

Which beta-blocker would you start?<br />

Do you follow the NT-proBNP?<br />

How high would the creatinine have to be before you would<br />

not start an ACE-I?<br />

Is there anyone who would start an ARB first? What if the<br />

patient was Asian?<br />

What other tests are needed before discharge?<br />

What do you use as discharge criteria?<br />

Does he need a heart failure cardiologist to follow him?<br />

Would you evaluate his hypertension? Would his race matter<br />

in this answer?<br />

Would you start a statin? If so, which one and at what dose?<br />

7:20 Case 2 & FAQs:<br />

55-year-old woman has been followed for a dilated cardiomyopathy<br />

for several years by a board-certified advanced<br />

heart failure cardiologist and is on evidence-based therapy<br />

at the highest tolerated doses. She has had to stop working<br />

as a teacher, and is only able to do light chores at home.<br />

She is not volume overloaded but is profoundly fatigued.<br />

She has a single-lead ICD. Her BP is 90/50 mmHg, and her<br />

heart rate is 55 bpm. Renal function is normal.<br />

Would you order a VO2 max?<br />

Would you perform a right heart cath?<br />

Would you perform a left heart cath?<br />

Is there a role for MRI now?<br />

Would you order any biomarkers? If so, which ones?<br />

Would you admit her to the hospital?<br />

What hemodynamics would compel you to decrease her<br />

medications?<br />

What hemodynamics would compel you to add medicines?<br />

What circumstances would compel you to add an inotrope?<br />

What triggers do you use to initiate a transplant evaluation?<br />

What is your weight cut-off for transplant? How about for<br />

VAD?<br />

What is your age cut-off for transplant?<br />

7:40 Case 3 & FAQs:<br />

55 year old male has a dilated cardiomyopathy for unclear<br />

reasons. He has refused left heart cath in the past.<br />

He has long standing hypertension, recent diabetes and is<br />

a 40 pack year cigarette smoker. He is now admitted with<br />

acute decompensated heart failure. He is approximately 20<br />

pounds increased from his last office visit weight. His BP<br />

is 90/50mmg, heart rate 110/min, somewhat irregular. On<br />

examination, he is warm and volume overloaded. Renal<br />

function is normal. In the emergency room, he is given 40<br />

IV furosemide with little urine output over the next hour.<br />

Would you give a higher dose of furosemide?<br />

Would you give a thiazide diuretic like metalozone?<br />

Is there a role for nesiritide?<br />

When would you consider invasive hemodynamic testing?<br />

Does he need admission?<br />

Does your program transplant active cigarette smokers?<br />

How about marijuana?<br />

How high would a troponin have to be before you take him<br />

to the cath lab?<br />

8:00 Additional Audience FAQs<br />

8:00 Adjourn<br />

Learning objective: Identify important decision points in<br />

drug therapy for heart failure, and describe effective management<br />

strategies.<br />

Abstracts/posters of interest: 102, 98, 99, 96, 97, 101, 103<br />

8:30 AM – 10:00 AM<br />

Maryland B<br />

Case Discussion – Clinical Conundrums<br />

Moderators: Sara Paul, Hickory, NC<br />

Lynne Warner Stevenson, Boston MA<br />

Panelists:<br />

Robert DiDomenico, Chicago, IL<br />

Joseph Hill, Dallas, TX<br />

Alan Miller, Jacksonville, FL<br />

Christine Thompson, Stanford CA<br />

Sana Al-Khatib, Durham, SC<br />

10:00 Adjourn<br />

Learning Objective: Using practice guidelines, research<br />

findings, and clinical experience, make management decisions<br />

about difficult cases in heart failure.<br />

47

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