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the Virus<br />
that<br />
owns the<br />
world<br />
Story Maryalice Yakutchik<br />
Illustration Dung Hoang<br />
Keerti Shah’s got nothing against the human papillomavirus.<br />
The virolog<strong>is</strong>t bears no grudge against the virus that causes half a<br />
million cervical cancers worldwide every year and now <strong>is</strong> blamed for a<br />
r<strong>is</strong>e in head and neck cancers so surpr<strong>is</strong>ingly sharp that it may presage<br />
an imminent epidemic among U.S. baby boomers.<br />
Revered for h<strong>is</strong> Zen-like attitude as well as a body of research that<br />
has spanned six decades and spawned stunning d<strong>is</strong>coveries about HPV’s<br />
cancer-causing ways, Shah simply <strong>is</strong> not the type to harbor ill will. Not<br />
against anyone or anything. Not even a bug that currently infects about<br />
79 million Americans and will infect, at some point in their lives, almost<br />
every sexually active person. Especially not a bug that’s so successfully<br />
infectious.<br />
In fact, Shah respects HPV. Not in the arched-eyebrow way you<br />
would an archrival, but with a fondness that belies kinship. A mere<br />
genetic snippet, and therefore in need of others’ cells to live, HPV just<br />
wants to communicate bits of itself. Survival requires transm<strong>is</strong>sion,<br />
replication.<br />
“The viruses are not devious,” says Shah, h<strong>is</strong> contagious smile<br />
conveying empathy. Papillomaviruses, he explains, have co-ex<strong>is</strong>ted quite<br />
peacefully with humans throughout time and relatively rarely do harm.<br />
Johns hopkins public <strong>health</strong> / spring 2013 23