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Sparks of Inhalation Innovation

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22<br />

Feature<br />

In an industry as diverse as pharmaceuticals, there is much<br />

that different disciplines can learn from each another.<br />

Here, I present a few potential sparks <strong>of</strong> inspiration by asking if<br />

and how the world <strong>of</strong> drug delivery can benefit from a more holistic<br />

use <strong>of</strong> the innovations occurring all around us – and vice versa.<br />

By Richard N. Dalby<br />

According to the US Department <strong>of</strong> Commerce (1),<br />

the US is the largest medical device market in the<br />

world and is expected to be valued at over $130 billion<br />

by 2016. The same source reports that there are<br />

more than 6,500 medical device companies in the US. I am<br />

a co-organizer <strong>of</strong> the Respiratory Drug Delivery (RDD)<br />

meetings and it occurred to me that there is much that my<br />

field could teach medical device developers in other areas.<br />

For example, could some <strong>of</strong> the latest advances in inhaler<br />

technology be applied to the development <strong>of</strong> autoinjectors<br />

or influence the design <strong>of</strong> new devices? Conversely, could<br />

innovations in other medical devices affect the development <strong>of</strong><br />

platforms to administer inhaled drugs? Ultimately, combining<br />

all <strong>of</strong> our knowledge and learning could be beneficial to both<br />

pharmaceutical development and patients.<br />

Our RDD conferences have traditionally addressed<br />

contemporary science issues that affect combination products<br />

(hardware and drug-containing formulation packaged together),<br />

but the science we cover extends far beyond pulmonary and nasal<br />

inhalation products; in part, because the conferences showcase<br />

innovations that have applications for other pharmaceutical<br />

solid, non-aqueous and aqueous liquids, and dispersed systems<br />

– for both small and large molecules. The technologies created<br />

in the inhalation industry have enabled developments at many<br />

companies making injectors, novel parenteral formulations,<br />

biopharmaceuticals and specialty orphan products.

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